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STRINGSTRING
TOP2B TOP2B TOP2A TOP2A SLC2A10 SLC2A10 ENSG00000251357 ENSG00000251357 SLC2A8 SLC2A8 SLC2A13 SLC2A13 SLC2A12 SLC2A12 SLC2A6 SLC2A6
"ENSG00000251357" - Uncharacterized protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSG00000251357Uncharacterized protein (176 aa)    
Predicted Functional Partners:
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8; Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity) (477 aa)
    score_image       score_image   0.560
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity (507 aa)
    score_image       score_image   0.557
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter (541 aa)
    score_image       score_image   0.552
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12; Facilitative glucose transporter (By similarity) (617 aa)
    score_image       score_image   0.541
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers (648 aa)
    score_image       score_image   0.515
TOP2A
topoisomerase (DNA) II alpha 170kDa (1531 aa)
            score_image   0.493
TOP2B
topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene (1621 aa)
            score_image   0.493
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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