Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | KBTBD8 | kelch repeat and BTB (POZ) domain containing 8 (601 aa) | ||||||||||||
Predicted Functional Partners:
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 | ANKRD60 | ankyrin repeat domain 60 (345 aa) |
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0.725 | ||||||||||
 | MRPS14 | mitochondrial ribosomal protein S14 (128 aa) |
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0.506 | ||||||||||
 | UBC | ubiquitin C (685 aa) |
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0.498 | |||||||||
 | KLHDC1 | kelch domain containing 1 (406 aa) |
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0.482 | |||||||||
 | ZADH2 | zinc binding alcohol dehydrogenase domain containing 2 (377 aa) |
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0.477 | ||||||||||
 | B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2; Beta-1,3-N-acetylgalactosaminyltransferase active in synthesizing a unique carbohydrate structure, GalNAc-beta-1- 3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate (500 aa) |
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0.462 | ||||||||||
 | ZNF462 | zinc finger protein 462; May be involved in transcriptional regulation (2506 aa) |
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0.430 | |||||||||
 | KLHDC7A | kelch domain containing 7A (777 aa) |
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0.426 | |||||||||
 | GTDC2 | glycosyltransferase-like domain containing 2 (580 aa) |
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0.422 | ||||||||||
 | YPEL3 | yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity) (157 aa) |
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0.409 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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