node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHST14 | ZNF469 | ENSP00000307297 | ENSP00000402343 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Additi [...] | zinc finger protein 469; May be involved in transcriptional regulation | 0.760 |
DDX20 | ZNF469 | ENSP00000358716 | ENSP00000402343 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs | zinc finger protein 469; May be involved in transcriptional regulation | 0.615 |
GANAB | PLOD2 | ENSP00000340466 | ENSP00000282903 | glucosidase, alpha; neutral AB; Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | 0.411 |
GANAB | ZNF469 | ENSP00000340466 | ENSP00000402343 | glucosidase, alpha; neutral AB; Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins | zinc finger protein 469; May be involved in transcriptional regulation | 0.615 |
HNRNPM | ZNF469 | ENSP00000325376 | ENSP00000402343 | heterogeneous nuclear ribonucleoprotein M; Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines | zinc finger protein 469; May be involved in transcriptional regulation | 0.615 |
IFT88 | ZNF469 | ENSP00000323580 | ENSP00000402343 | intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity) | zinc finger protein 469; May be involved in transcriptional regulation | 0.615 |
IMMT | ZNF469 | ENSP00000387262 | ENSP00000402343 | inner membrane protein, mitochondrial | zinc finger protein 469; May be involved in transcriptional regulation | 0.615 |
P4HA3 | ZNF469 | ENSP00000332170 | ENSP00000402343 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | zinc finger protein 469; May be involved in transcriptional regulation | 0.636 |
PLOD2 | GANAB | ENSP00000282903 | ENSP00000340466 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | glucosidase, alpha; neutral AB; Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins | 0.411 |
PLOD2 | ZNF469 | ENSP00000282903 | ENSP00000402343 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | zinc finger protein 469; May be involved in transcriptional regulation | 0.643 |
PRMT2 | ZNF469 | ENSP00000347906 | ENSP00000402343 | protein arginine methyltransferase 2; Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1- dependent manner). May be involved in growth regulation | zinc finger protein 469; May be involved in transcriptional regulation | 0.629 |
UBAP2 | ZNF469 | ENSP00000354039 | ENSP00000402343 | ubiquitin associated protein 2 | zinc finger protein 469; May be involved in transcriptional regulation | 0.615 |
ZNF469 | CHST14 | ENSP00000402343 | ENSP00000307297 | zinc finger protein 469; May be involved in transcriptional regulation | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Additi [...] | 0.760 |
ZNF469 | DDX20 | ENSP00000402343 | ENSP00000358716 | zinc finger protein 469; May be involved in transcriptional regulation | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs | 0.615 |
ZNF469 | GANAB | ENSP00000402343 | ENSP00000340466 | zinc finger protein 469; May be involved in transcriptional regulation | glucosidase, alpha; neutral AB; Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins | 0.615 |
ZNF469 | HNRNPM | ENSP00000402343 | ENSP00000325376 | zinc finger protein 469; May be involved in transcriptional regulation | heterogeneous nuclear ribonucleoprotein M; Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines | 0.615 |
ZNF469 | IFT88 | ENSP00000402343 | ENSP00000323580 | zinc finger protein 469; May be involved in transcriptional regulation | intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity) | 0.615 |
ZNF469 | IMMT | ENSP00000402343 | ENSP00000387262 | zinc finger protein 469; May be involved in transcriptional regulation | inner membrane protein, mitochondrial | 0.615 |
ZNF469 | P4HA3 | ENSP00000402343 | ENSP00000332170 | zinc finger protein 469; May be involved in transcriptional regulation | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.636 |
ZNF469 | PLOD2 | ENSP00000402343 | ENSP00000282903 | zinc finger protein 469; May be involved in transcriptional regulation | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | 0.643 |