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MITD1 MITD1 TBCC TBCC TBCEL TBCEL ARL13A ARL13A TBCD TBCD TBCB TBCB RP2 RP2 TBCA TBCA ARL2 ARL2
"TBCEL" - tubulin folding cofactor E-like in Homo sapiens
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TBCELtubulin folding cofactor E-like; Acts as a regulator of tubulin stability (424 aa)    
Predicted Functional Partners:
TBCC
tubulin folding cofactor C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway (346 aa)
            score_image   0.912
TBCD
tubulin folding cofactor D (1192 aa)
            score_image   0.884
MITD1
MIT, microtubule interacting and transport, domain containing 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex (249 aa)
            score_image   0.643
RP2
retinitis pigmentosa 2 (X-linked recessive); Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins (350 aa)
            score_image   0.541
ARL13A
ADP-ribosylation factor-like 13A (256 aa)
            score_image   0.485
ARL2
ADP-ribosylation factor-like 2; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of T [...] (184 aa)
            score_image   0.485
TBCA
tubulin folding cofactor A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway (108 aa)
            score_image   0.485
TBCB
tubulin folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth (244 aa)
            score_image   0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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