SPANXN4 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Score

SPANXN4

SPANX family, member N4 (99 aa)

Predicted Functional Partners:

MAGEC3

0.510

SNURFL

0.506

CXorf66

0.501

SRPK1

0.461

PNMA6A

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

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same PNG format, but resolution at 400 dpi

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXorf66	PNMA6A	ENSP00000359571	ENSP00000405718	chromosome X open reading frame 66	paraneoplastic Ma antigen family member 6A	0.405
CXorf66	SNURFL	ENSP00000359571	ENSP00000311181	chromosome X open reading frame 66	SNRPN upstream reading frame-like	0.505
CXorf66	SPANXN4	ENSP00000359571	ENSP00000405210	chromosome X open reading frame 66	SPANX family, member N4	0.501
MAGEC3	SPANXN4	ENSP00000298296	ENSP00000405210	melanoma antigen family C, 3	SPANX family, member N4	0.510
PNMA6A	CXorf66	ENSP00000405718	ENSP00000359571	paraneoplastic Ma antigen family member 6A	chromosome X open reading frame 66	0.405
PNMA6A	SNURFL	ENSP00000405718	ENSP00000311181	paraneoplastic Ma antigen family member 6A	SNRPN upstream reading frame-like	0.416
PNMA6A	SPANXN4	ENSP00000405718	ENSP00000405210	paraneoplastic Ma antigen family member 6A	SPANX family, member N4	0.407
SNURFL	CXorf66	ENSP00000311181	ENSP00000359571	SNRPN upstream reading frame-like	chromosome X open reading frame 66	0.505
SNURFL	PNMA6A	ENSP00000311181	ENSP00000405718	SNRPN upstream reading frame-like	paraneoplastic Ma antigen family member 6A	0.416
SNURFL	SPANXN4	ENSP00000311181	ENSP00000405210	SNRPN upstream reading frame-like	SPANX family, member N4	0.506
SPANXN4	CXorf66	ENSP00000405210	ENSP00000359571	SPANX family, member N4	chromosome X open reading frame 66	0.501
SPANXN4	MAGEC3	ENSP00000405210	ENSP00000298296	SPANX family, member N4	melanoma antigen family C, 3	0.510
SPANXN4	PNMA6A	ENSP00000405210	ENSP00000405718	SPANX family, member N4	paraneoplastic Ma antigen family member 6A	0.407
SPANXN4	SNURFL	ENSP00000405210	ENSP00000311181	SPANX family, member N4	SNRPN upstream reading frame-like	0.506
SPANXN4	SRPK1	ENSP00000405210	ENSP00000362931	SPANX family, member N4	SRSF protein kinase 1; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Can influence additional steps of mRNA maturation, as well as other cellular activiti [...]	0.461
SRPK1	SPANXN4	ENSP00000362931	ENSP00000405210	SRSF protein kinase 1; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Can influence additional steps of mRNA maturation, as well as other cellular activiti [...]	SPANX family, member N4	0.461

Experiments

Cooccurrence

Textmining

Neighborhood

Databases

Fusion

Coexpression

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