| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BANF1 | H2AFV | ENSP00000310275 | ENSP00000308405 | barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Associat [...] | H2A histone family, member V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | 0.405 |
| BANF1 | H2AFZ | ENSP00000310275 | ENSP00000296417 | barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Associat [...] | H2A histone family, member Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | 0.447 |
| BANF1 | IFLTD1 | ENSP00000310275 | ENSP00000407353 | barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Associat [...] | intermediate filament tail domain containing 1 | 0.640 |
| BANF2 | IFLTD1 | ENSP00000439128 | ENSP00000407353 | barrier to autointegration factor 2; May play a role in BANF1 regulation and influence tissue-specific roles of BANF1 | intermediate filament tail domain containing 1 | 0.640 |
| BICD1 | IFLTD1 | ENSP00000281474 | ENSP00000407353 | bicaudal D homolog 1 (Drosophila); Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex | intermediate filament tail domain containing 1 | 0.602 |
| BICD2 | IFLTD1 | ENSP00000349351 | ENSP00000407353 | bicaudal D homolog 2 (Drosophila); May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex (By similarity) | intermediate filament tail domain containing 1 | 0.602 |
| CASC1 | IFLTD1 | ENSP00000379310 | ENSP00000407353 | cancer susceptibility candidate 1 | intermediate filament tail domain containing 1 | 0.757 |
| CASC1 | LYRM5 | ENSP00000379310 | ENSP00000370761 | cancer susceptibility candidate 1 | LYR motif containing 5 | 0.424 |
| H2AFV | BANF1 | ENSP00000308405 | ENSP00000310275 | H2A histone family, member V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Associat [...] | 0.405 |
| H2AFV | IFLTD1 | ENSP00000308405 | ENSP00000407353 | H2A histone family, member V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | intermediate filament tail domain containing 1 | 0.652 |
| H2AFZ | BANF1 | ENSP00000296417 | ENSP00000310275 | H2A histone family, member Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Associat [...] | 0.447 |
| H2AFZ | IFLTD1 | ENSP00000296417 | ENSP00000407353 | H2A histone family, member Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | intermediate filament tail domain containing 1 | 0.652 |
| IFLTD1 | BANF1 | ENSP00000407353 | ENSP00000310275 | intermediate filament tail domain containing 1 | barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Associat [...] | 0.640 |
| IFLTD1 | BANF2 | ENSP00000407353 | ENSP00000439128 | intermediate filament tail domain containing 1 | barrier to autointegration factor 2; May play a role in BANF1 regulation and influence tissue-specific roles of BANF1 | 0.640 |
| IFLTD1 | BICD1 | ENSP00000407353 | ENSP00000281474 | intermediate filament tail domain containing 1 | bicaudal D homolog 1 (Drosophila); Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex | 0.602 |
| IFLTD1 | BICD2 | ENSP00000407353 | ENSP00000349351 | intermediate filament tail domain containing 1 | bicaudal D homolog 2 (Drosophila); May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex (By similarity) | 0.602 |
| IFLTD1 | CASC1 | ENSP00000407353 | ENSP00000379310 | intermediate filament tail domain containing 1 | cancer susceptibility candidate 1 | 0.757 |
| IFLTD1 | H2AFV | ENSP00000407353 | ENSP00000308405 | intermediate filament tail domain containing 1 | H2A histone family, member V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | 0.652 |
| IFLTD1 | H2AFZ | ENSP00000407353 | ENSP00000296417 | intermediate filament tail domain containing 1 | H2A histone family, member Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] | 0.652 |
| IFLTD1 | LYRM5 | ENSP00000407353 | ENSP00000370761 | intermediate filament tail domain containing 1 | LYR motif containing 5 | 0.720 |
Share
