node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGAP10 | HEATR1 | ENSP00000407436 | ENSP00000355541 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | 0.978 |
AGAP10 | MPHOSPH10 | ENSP00000407436 | ENSP00000244230 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | 0.979 |
AGAP10 | NAT10 | ENSP00000407436 | ENSP00000257829 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | N-acetyltransferase 10 (GCN5-related); Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division | 0.989 |
AGAP10 | NOL10 | ENSP00000407436 | ENSP00000371101 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | nucleolar protein 10 | 0.990 |
AGAP10 | NOP14 | ENSP00000407436 | ENSP00000315674 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) | 0.992 |
AGAP10 | PDCD11 | ENSP00000407436 | ENSP00000358812 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA | 0.978 |
AGAP10 | RBM19 | ENSP00000407436 | ENSP00000261741 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) | 0.978 |
AGAP10 | RRP12 | ENSP00000407436 | ENSP00000360031 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.988 |
AGAP10 | WDR36 | ENSP00000407436 | ENSP00000423067 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 | 0.982 |
AGAP10 | WDR75 | ENSP00000407436 | ENSP00000314193 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | WD repeat domain 75 | 0.975 |
HEATR1 | AGAP10 | ENSP00000355541 | ENSP00000407436 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) | 0.978 |
HEATR1 | MPHOSPH10 | ENSP00000355541 | ENSP00000244230 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | 0.994 |
HEATR1 | NAT10 | ENSP00000355541 | ENSP00000257829 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | N-acetyltransferase 10 (GCN5-related); Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division | 0.991 |
HEATR1 | NOL10 | ENSP00000355541 | ENSP00000371101 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | nucleolar protein 10 | 0.869 |
HEATR1 | NOP14 | ENSP00000355541 | ENSP00000315674 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) | 0.994 |
HEATR1 | PDCD11 | ENSP00000355541 | ENSP00000358812 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA | 0.994 |
HEATR1 | RBM19 | ENSP00000355541 | ENSP00000261741 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) | 0.920 |
HEATR1 | RRP12 | ENSP00000355541 | ENSP00000360031 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.995 |
HEATR1 | WDR36 | ENSP00000355541 | ENSP00000423067 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 | 0.999 |
HEATR1 | WDR75 | ENSP00000355541 | ENSP00000314193 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | WD repeat domain 75 | 0.998 |