node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DISC1 | KIF5A | ENSP00000355593 | ENSP00000408979 | disrupted in schizophrenia 1 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | 0.836 |
DISC1 | NDEL1 | ENSP00000355593 | ENSP00000333982 | disrupted in schizophrenia 1 | nudE nuclear distribution E homolog (A. nidulans)-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integri [...] | 0.998 |
ENSG00000256500 | KIF5A | ENSP00000439065 | ENSP00000408979 | Kinesin light chain 1 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | 0.913 |
ENSG00000256500 | TRAK1 | ENSP00000439065 | ENSP00000328998 | Kinesin light chain 1 | trafficking protein, kinesin binding 1; Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors | 0.642 |
KIF26A | KIF5A | ENSP00000388241 | ENSP00000408979 | kinesin family member 26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity) | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | 0.922 |
KIF26A | KLC1 | ENSP00000388241 | ENSP00000414982 | kinesin family member 26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity) | kinesin light chain 1 | 0.921 |
KIF26A | KLC2 | ENSP00000388241 | ENSP00000314837 | kinesin family member 26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity) | kinesin light chain 2; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity) | 0.913 |
KIF5A | DISC1 | ENSP00000408979 | ENSP00000355593 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | disrupted in schizophrenia 1 | 0.836 |
KIF5A | ENSG00000256500 | ENSP00000408979 | ENSP00000439065 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | Kinesin light chain 1 | 0.913 |
KIF5A | KIF26A | ENSP00000408979 | ENSP00000388241 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | kinesin family member 26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity) | 0.922 |
KIF5A | KLC1 | ENSP00000408979 | ENSP00000414982 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | kinesin light chain 1 | 0.999 |
KIF5A | KLC2 | ENSP00000408979 | ENSP00000314837 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | kinesin light chain 2; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity) | 0.999 |
KIF5A | KLC3 | ENSP00000408979 | ENSP00000375810 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport | 0.846 |
KIF5A | KLC4 | ENSP00000408979 | ENSP00000259708 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | kinesin light chain 4; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity) | 0.998 |
KIF5A | NDEL1 | ENSP00000408979 | ENSP00000333982 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | nudE nuclear distribution E homolog (A. nidulans)-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integri [...] | 0.891 |
KIF5A | TRAK1 | ENSP00000408979 | ENSP00000328998 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | trafficking protein, kinesin binding 1; Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors | 0.902 |
KIF5A | ZFYVE27 | ENSP00000408979 | ENSP00000348593 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | zinc finger, FYVE domain containing 27 | 0.840 |
KLC1 | KIF26A | ENSP00000414982 | ENSP00000388241 | kinesin light chain 1 | kinesin family member 26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity) | 0.921 |
KLC1 | KIF5A | ENSP00000414982 | ENSP00000408979 | kinesin light chain 1 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | 0.999 |
KLC1 | KLC2 | ENSP00000414982 | ENSP00000314837 | kinesin light chain 1 | kinesin light chain 2; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity) | 0.999 |