ACADM protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 (425 aa)

Predicted Functional Partners:

HADHA

0.994

EHHADH

0.993

HADHB

0.984

ACAA2

0.981

ECHS1

0.979

ACAA1

0.975

ETFA

0.975

ACAT2

0.969

ACAT1

0.966

ECHDC1

0.962

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACADM	ENSP00000333664	ENSP00000409612	acetyl-CoA acyltransferase 1	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	0.975
ACAA1	ACAT1	ENSP00000333664	ENSP00000265838	acetyl-CoA acyltransferase 1	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.924
ACAA1	ACAT2	ENSP00000333664	ENSP00000356015	acetyl-CoA acyltransferase 1	acetyl-CoA acetyltransferase 2	0.911
ACAA1	ECHDC1	ENSP00000333664	ENSP00000436585	acetyl-CoA acyltransferase 1	enoyl CoA hydratase domain containing 1	0.947
ACAA1	ECHS1	ENSP00000333664	ENSP00000357535	acetyl-CoA acyltransferase 1	enoyl CoA hydratase, short chain, 1, mitochondrial; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate	0.867
ACAA1	EHHADH	ENSP00000333664	ENSP00000231887	acetyl-CoA acyltransferase 1	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	0.998
ACAA1	HADHA	ENSP00000333664	ENSP00000370023	acetyl-CoA acyltransferase 1	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit	0.999
ACAA2	ACADM	ENSP00000285093	ENSP00000409612	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	0.981
ACAA2	ACAT1	ENSP00000285093	ENSP00000265838	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.972
ACAA2	ACAT2	ENSP00000285093	ENSP00000356015	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acetyl-CoA acetyltransferase 2	0.908
ACAA2	ECHDC1	ENSP00000285093	ENSP00000436585	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	enoyl CoA hydratase domain containing 1	0.949
ACAA2	ECHS1	ENSP00000285093	ENSP00000357535	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	enoyl CoA hydratase, short chain, 1, mitochondrial; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate	0.899
ACAA2	EHHADH	ENSP00000285093	ENSP00000231887	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	0.998
ACAA2	ETFA	ENSP00000285093	ENSP00000452762	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	electron-transfer-flavoprotein, alpha polypeptide; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)	0.469
ACAA2	HADHA	ENSP00000285093	ENSP00000370023	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit	0.999
ACADM	ACAA1	ENSP00000409612	ENSP00000333664	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acyltransferase 1	0.975
ACADM	ACAA2	ENSP00000409612	ENSP00000285093	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	0.981
ACADM	ACAT1	ENSP00000409612	ENSP00000265838	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.966
ACADM	ACAT2	ENSP00000409612	ENSP00000356015	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acetyltransferase 2	0.969
ACADM	ECHDC1	ENSP00000409612	ENSP00000436585	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	enoyl CoA hydratase domain containing 1	0.962

page 1 of 6

Experiments

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About