| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FAM131B | ZNF783 | ENSP00000410603 | ENSP00000410890 | family with sequence similarity 131, member B | zinc finger family member 783; May be involved in transcriptional regulation | 0.499 |
| FBXL19 | ZNF212 | ENSP00000369666 | ENSP00000338572 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 212; May be involved in transcriptional regulation | 0.501 |
| FBXL19 | ZNF398 | ENSP00000369666 | ENSP00000420418 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 398; Function as a transcriptional activator | 0.501 |
| FBXL19 | ZNF783 | ENSP00000369666 | ENSP00000410890 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger family member 783; May be involved in transcriptional regulation | 0.501 |
| HRASLS5 | ZNF783 | ENSP00000301790 | ENSP00000410890 | HRAS-like suppressor family, member 5; catalyzes N-acylation of phosphatidylethanolamine (PE) to generate N-Acylphosphatidylethanolamine (NAPE) a precursor of bioactive N-acylethanolamines, including the endocannabinoid anandamide | zinc finger family member 783; May be involved in transcriptional regulation | 0.576 |
| KDM2A | ZNF212 | ENSP00000432786 | ENSP00000338572 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 212; May be involved in transcriptional regulation | 0.501 |
| KDM2A | ZNF398 | ENSP00000432786 | ENSP00000420418 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 398; Function as a transcriptional activator | 0.501 |
| KDM2A | ZNF783 | ENSP00000432786 | ENSP00000410890 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger family member 783; May be involved in transcriptional regulation | 0.501 |
| KDM2B | ZNF212 | ENSP00000366271 | ENSP00000338572 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 212; May be involved in transcriptional regulation | 0.501 |
| KDM2B | ZNF398 | ENSP00000366271 | ENSP00000420418 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 398; Function as a transcriptional activator | 0.501 |
| KDM2B | ZNF783 | ENSP00000366271 | ENSP00000410890 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger family member 783; May be involved in transcriptional regulation | 0.501 |
| LRRC61 | ZNF783 | ENSP00000339047 | ENSP00000410890 | leucine rich repeat containing 61 | zinc finger family member 783; May be involved in transcriptional regulation | 0.517 |
| PRDM7 | ZNF783 | ENSP00000396732 | ENSP00000410890 | PR domain containing 7; Probable histone methyltransferase (By similarity) | zinc finger family member 783; May be involved in transcriptional regulation | 0.528 |
| XRN1 | ZNF212 | ENSP00000264951 | ENSP00000338572 | 5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) | zinc finger protein 212; May be involved in transcriptional regulation | 0.543 |
| XRN1 | ZNF398 | ENSP00000264951 | ENSP00000420418 | 5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) | zinc finger protein 398; Function as a transcriptional activator | 0.543 |
| XRN1 | ZNF783 | ENSP00000264951 | ENSP00000410890 | 5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) | zinc finger family member 783; May be involved in transcriptional regulation | 0.543 |
| ZNF212 | FBXL19 | ENSP00000338572 | ENSP00000369666 | zinc finger protein 212; May be involved in transcriptional regulation | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | 0.501 |
| ZNF212 | KDM2A | ENSP00000338572 | ENSP00000432786 | zinc finger protein 212; May be involved in transcriptional regulation | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | 0.501 |
| ZNF212 | KDM2B | ENSP00000338572 | ENSP00000366271 | zinc finger protein 212; May be involved in transcriptional regulation | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | 0.501 |
| ZNF212 | XRN1 | ENSP00000338572 | ENSP00000264951 | zinc finger protein 212; May be involved in transcriptional regulation | 5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) | 0.543 |
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