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STRINGSTRING
ZNF674 ZNF674 SYT16 SYT16 SKIDA1 SKIDA1 ZNF304 ZNF304 TMPRSS7 TMPRSS7 ASCC2 ASCC2 FBXL6 FBXL6 CDCA7 CDCA7 MOCS1 MOCS1 ZNF239 ZNF239 PPP3CA PPP3CA
"TMPRSS7" - transmembrane protease, serine 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS7transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) (717 aa)    
Predicted Functional Partners:
FBXL6
F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) (539 aa)
            score_image   0.748
ZNF239
zinc finger protein 239; May be involved in transcriptional regulation (458 aa)
            score_image   0.704
MOCS1
molybdenum cofactor synthesis 1 (385 aa)
            score_image   0.686
SKIDA1
SKI/DACH domain containing 1 (908 aa)
            score_image   0.565
CDCA7
cell division cycle associated 7; Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator (450 aa)
            score_image   0.523
ASCC2
activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation (757 aa)
            score_image   0.507
ZNF674
zinc finger protein 674; May be involved in transcriptional regulation (581 aa)
            score_image   0.479
SYT16
synaptotagmin XVI; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent (645 aa)
            score_image   0.471
ZNF304
zinc finger protein 304; May be involved in transcriptional regulation (659 aa)
            score_image   0.459
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1 (521 aa)
            score_image   0.438
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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