node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASCC2 | TMPRSS7 | ENSP00000305502 | ENSP00000411645 | activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.507 |
CDCA7 | FBXL6 | ENSP00000306968 | ENSP00000330098 | cell division cycle associated 7; Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | 0.449 |
CDCA7 | TMPRSS7 | ENSP00000306968 | ENSP00000411645 | cell division cycle associated 7; Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.523 |
CDCA7 | ZNF239 | ENSP00000306968 | ENSP00000307774 | cell division cycle associated 7; Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator | zinc finger protein 239; May be involved in transcriptional regulation | 0.506 |
FBXL6 | CDCA7 | ENSP00000330098 | ENSP00000306968 | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | cell division cycle associated 7; Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator | 0.449 |
FBXL6 | MOCS1 | ENSP00000330098 | ENSP00000362282 | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | molybdenum cofactor synthesis 1 | 0.573 |
FBXL6 | TMPRSS7 | ENSP00000330098 | ENSP00000411645 | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.748 |
FBXL6 | ZNF239 | ENSP00000330098 | ENSP00000307774 | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 239; May be involved in transcriptional regulation | 0.681 |
MOCS1 | FBXL6 | ENSP00000362282 | ENSP00000330098 | molybdenum cofactor synthesis 1 | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | 0.573 |
MOCS1 | TMPRSS7 | ENSP00000362282 | ENSP00000411645 | molybdenum cofactor synthesis 1 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.686 |
MOCS1 | ZNF239 | ENSP00000362282 | ENSP00000307774 | molybdenum cofactor synthesis 1 | zinc finger protein 239; May be involved in transcriptional regulation | 0.627 |
PPP3CA | TMPRSS7 | ENSP00000378323 | ENSP00000411645 | protein phosphatase 3, catalytic subunit, alpha isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.438 |
PPP3CA | ZNF239 | ENSP00000378323 | ENSP00000307774 | protein phosphatase 3, catalytic subunit, alpha isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1 | zinc finger protein 239; May be involved in transcriptional regulation | 0.524 |
SKIDA1 | TMPRSS7 | ENSP00000410041 | ENSP00000411645 | SKI/DACH domain containing 1 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.565 |
SYT16 | TMPRSS7 | ENSP00000394700 | ENSP00000411645 | synaptotagmin XVI; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | 0.471 |
TMPRSS7 | ASCC2 | ENSP00000411645 | ENSP00000305502 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | 0.507 |
TMPRSS7 | CDCA7 | ENSP00000411645 | ENSP00000306968 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | cell division cycle associated 7; Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator | 0.523 |
TMPRSS7 | FBXL6 | ENSP00000411645 | ENSP00000330098 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | F-box and leucine-rich repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | 0.748 |
TMPRSS7 | MOCS1 | ENSP00000411645 | ENSP00000362282 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | molybdenum cofactor synthesis 1 | 0.686 |
TMPRSS7 | PPP3CA | ENSP00000411645 | ENSP00000378323 | transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity) | protein phosphatase 3, catalytic subunit, alpha isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1 | 0.438 |