| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C19orf47 | PRR13 | ENSP00000463159 | ENSP00000412064 | chromosome 19 open reading frame 47 | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | 0.499 |
| C19orf47 | TTC9B | ENSP00000463159 | ENSP00000311760 | chromosome 19 open reading frame 47 | tetratricopeptide repeat domain 9B | 0.757 |
| CD47 | DUSP12 | ENSP00000355361 | ENSP00000356920 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | dual specificity phosphatase 12 | 0.440 |
| CD47 | PRR13 | ENSP00000355361 | ENSP00000412064 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | 0.741 |
| CD47 | THBS1 | ENSP00000355361 | ENSP00000260356 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | thrombospondin 1; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties | 0.998 |
| CD47 | THBS2 | ENSP00000355361 | ENSP00000355751 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | thrombospondin 2; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties | 0.862 |
| DUSP1 | ITGA9 | ENSP00000239223 | ENSP00000264741 | dual specificity phosphatase 1; Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both ’Thr-183’ and ’Tyr-185’, regulating its activity during the meiotic cell cycle (By similarity) | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | 0.416 |
| DUSP1 | PRR13 | ENSP00000239223 | ENSP00000412064 | dual specificity phosphatase 1; Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both ’Thr-183’ and ’Tyr-185’, regulating its activity during the meiotic cell cycle (By similarity) | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | 0.562 |
| DUSP12 | CD47 | ENSP00000356920 | ENSP00000355361 | dual specificity phosphatase 12 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | 0.440 |
| DUSP12 | ITGA9 | ENSP00000356920 | ENSP00000264741 | dual specificity phosphatase 12 | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | 0.493 |
| DUSP12 | PRR13 | ENSP00000356920 | ENSP00000412064 | dual specificity phosphatase 12 | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | 0.652 |
| DUSP12 | THBS2 | ENSP00000356920 | ENSP00000355751 | dual specificity phosphatase 12 | thrombospondin 2; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties | 0.459 |
| DUSP12 | TYMP | ENSP00000356920 | ENSP00000252029 | dual specificity phosphatase 12 | thymidine phosphorylase; May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro | 0.454 |
| ITGA9 | DUSP1 | ENSP00000264741 | ENSP00000239223 | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | dual specificity phosphatase 1; Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both ’Thr-183’ and ’Tyr-185’, regulating its activity during the meiotic cell cycle (By similarity) | 0.416 |
| ITGA9 | DUSP12 | ENSP00000264741 | ENSP00000356920 | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | dual specificity phosphatase 12 | 0.493 |
| ITGA9 | PRR13 | ENSP00000264741 | ENSP00000412064 | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | 0.561 |
| ITGA9 | THBS1 | ENSP00000264741 | ENSP00000260356 | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | thrombospondin 1; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties | 0.897 |
| ITGA9 | THBS2 | ENSP00000264741 | ENSP00000355751 | integrin, alpha 9; Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin | thrombospondin 2; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties | 0.872 |
| PPIA | PRR13 | ENSP00000419425 | ENSP00000412064 | peptidylprolyl isomerase A (cyclophilin A); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | 0.506 |
| PRR13 | C19orf47 | ENSP00000412064 | ENSP00000463159 | proline rich 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis | chromosome 19 open reading frame 47 | 0.499 |
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