node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSG00000259024 | TMEM64 | ENSP00000429865 | ENSP00000414786 | FAM18B2-CDRT4 readthrough | transmembrane protein 64 | 0.491 |
FAM18A | TMEM64 | ENSP00000299866 | ENSP00000414786 | family with sequence similarity 18, member A | transmembrane protein 64 | 0.491 |
FAM18B1 | TMEM64 | ENSP00000305654 | ENSP00000414786 | family with sequence similarity 18, member B1 | transmembrane protein 64 | 0.491 |
FAM18B1 | UBC | ENSP00000305654 | ENSP00000344818 | family with sequence similarity 18, member B1 | ubiquitin C | 0.752 |
FBXO8 | FUBP3 | ENSP00000377280 | ENSP00000318177 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | 0.544 |
FBXO8 | KPNA3 | ENSP00000377280 | ENSP00000261667 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | karyopherin alpha 3 (importin alpha 4); Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alph [...] | 0.516 |
FBXO8 | LRCH1 | ENSP00000377280 | ENSP00000374447 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.577 |
FBXO8 | LRCH2 | ENSP00000377280 | ENSP00000325091 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | leucine-rich repeats and calponin homology (CH) domain containing 2 | 0.485 |
FBXO8 | SMARCD1 | ENSP00000377280 | ENSP00000378414 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1; Involved in chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subuni [...] | 0.508 |
FBXO8 | TMEM64 | ENSP00000377280 | ENSP00000414786 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | transmembrane protein 64 | 0.636 |
FBXO8 | UBC | ENSP00000377280 | ENSP00000344818 | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | ubiquitin C | 0.688 |
FUBP3 | FBXO8 | ENSP00000318177 | ENSP00000377280 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | 0.544 |
FUBP3 | KPNA3 | ENSP00000318177 | ENSP00000261667 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | karyopherin alpha 3 (importin alpha 4); Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alph [...] | 0.455 |
FUBP3 | LRCH1 | ENSP00000318177 | ENSP00000374447 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.532 |
FUBP3 | SMARCD1 | ENSP00000318177 | ENSP00000378414 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1; Involved in chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subuni [...] | 0.505 |
FUBP3 | TMEM64 | ENSP00000318177 | ENSP00000414786 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | transmembrane protein 64 | 0.573 |
FUBP3 | UBC | ENSP00000318177 | ENSP00000344818 | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | ubiquitin C | 0.849 |
KPNA3 | FBXO8 | ENSP00000261667 | ENSP00000377280 | karyopherin alpha 3 (importin alpha 4); Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alph [...] | F-box protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential) | 0.516 |
KPNA3 | FUBP3 | ENSP00000261667 | ENSP00000318177 | karyopherin alpha 3 (importin alpha 4); Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alph [...] | far upstream element (FUSE) binding protein 3; May interact with single-stranded DNA from the far- upstream element (FUSE). May activate gene expression | 0.455 |
KPNA3 | TMEM64 | ENSP00000261667 | ENSP00000414786 | karyopherin alpha 3 (importin alpha 4); Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alph [...] | transmembrane protein 64 | 0.522 |