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STRINGSTRING
SEPT4 SEPT4 BTG4 BTG4 C17orf105 C17orf105 SEPT5 SEPT5 SEPT1 SEPT1
"C17orf105" - chromosome 17 open reading frame 105 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C17orf105chromosome 17 open reading frame 105 (164 aa)    
Predicted Functional Partners:
BTG4
B-cell translocation gene 4; Shows marked antiproliferative activity, being able to induce G(1) arrest (223 aa)
            score_image   0.583
SEPT1
septin 1; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential) (367 aa)
            score_image   0.451
SEPT5
septin 5; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity) (369 aa)
            score_image   0.451
SEPT4
septin 4; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli (478 aa)
            score_image   0.451
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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