node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MUC1 | MUC12 | ENSP00000357380 | ENSP00000441929 | mucin 1, cell surface associated | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | 0.956 |
MUC1 | MUC13 | ENSP00000357380 | ENSP00000312235 | mucin 1, cell surface associated | mucin 13, cell surface associated; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling | 0.938 |
MUC1 | MUC15 | ENSP00000357380 | ENSP00000416753 | mucin 1, cell surface associated | mucin 15, cell surface associated; May play a role in the cell adhesion to the extracellular matrix | 0.973 |
MUC1 | MUC16 | ENSP00000357380 | ENSP00000381008 | mucin 1, cell surface associated | mucin 16, cell surface associated; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) | 0.971 |
MUC1 | MUC17 | ENSP00000357380 | ENSP00000302716 | mucin 1, cell surface associated | mucin 17, cell surface associated; Probably plays a role in maintaining homeostasis on mucosal surfaces | 0.954 |
MUC1 | MUC19 | ENSP00000357380 | ENSP00000395253 | mucin 1, cell surface associated | mucin 19, oligomeric; May function in ocular mucus homeostasis | 0.948 |
MUC1 | MUC20 | ENSP00000357380 | ENSP00000396774 | mucin 1, cell surface associated | mucin 20, cell surface associated; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression | 0.941 |
MUC1 | MUC3A | ENSP00000357380 | ENSP00000324834 | mucin 1, cell surface associated | mucin 3A, cell surface associated; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) | 0.937 |
MUC1 | MUC4 | ENSP00000357380 | ENSP00000417498 | mucin 1, cell surface associated | mucin 4, cell surface associated | 0.981 |
MUC1 | MUC7 | ENSP00000357380 | ENSP00000302021 | mucin 1, cell surface associated | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | 0.964 |
MUC12 | MUC1 | ENSP00000441929 | ENSP00000357380 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 1, cell surface associated | 0.956 |
MUC12 | MUC13 | ENSP00000441929 | ENSP00000312235 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 13, cell surface associated; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling | 0.962 |
MUC12 | MUC15 | ENSP00000441929 | ENSP00000416753 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 15, cell surface associated; May play a role in the cell adhesion to the extracellular matrix | 0.964 |
MUC12 | MUC16 | ENSP00000441929 | ENSP00000381008 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 16, cell surface associated; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) | 0.971 |
MUC12 | MUC17 | ENSP00000441929 | ENSP00000302716 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 17, cell surface associated; Probably plays a role in maintaining homeostasis on mucosal surfaces | 0.933 |
MUC12 | MUC19 | ENSP00000441929 | ENSP00000395253 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 19, oligomeric; May function in ocular mucus homeostasis | 0.968 |
MUC12 | MUC20 | ENSP00000441929 | ENSP00000396774 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 20, cell surface associated; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression | 0.956 |
MUC12 | MUC3A | ENSP00000441929 | ENSP00000324834 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 3A, cell surface associated; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) | 0.925 |
MUC12 | MUC4 | ENSP00000441929 | ENSP00000417498 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 4, cell surface associated | 0.928 |
MUC12 | MUC7 | ENSP00000441929 | ENSP00000302021 | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | 0.971 |