node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP1 | AQP7 | ENSP00000311165 | ENSP00000297988 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | aquaporin 7; Forms a channel for water and glycerol | 0.401 |
AQP1 | GK5 | ENSP00000311165 | ENSP00000418001 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | glycerol kinase 5 (putative) | 0.779 |
AQP1 | GPD2 | ENSP00000311165 | ENSP00000308610 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.673 |
AQP10 | AQP4 | ENSP00000318355 | ENSP00000372654 | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | 0.408 |
AQP10 | AQP5 | ENSP00000318355 | ENSP00000293599 | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions | 0.876 |
AQP10 | AQP6 | ENSP00000318355 | ENSP00000320247 | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | aquaporin 6, kidney specific; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism (By similarity) | 0.927 |
AQP10 | GK5 | ENSP00000318355 | ENSP00000418001 | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | glycerol kinase 5 (putative) | 0.791 |
AQP10 | GPD2 | ENSP00000318355 | ENSP00000308610 | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.671 |
AQP3 | AQP4 | ENSP00000297991 | ENSP00000372654 | aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...] | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | 0.412 |
AQP3 | GK5 | ENSP00000297991 | ENSP00000418001 | aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...] | glycerol kinase 5 (putative) | 0.791 |
AQP3 | GPD2 | ENSP00000297991 | ENSP00000308610 | aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...] | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.703 |
AQP4 | AQP10 | ENSP00000372654 | ENSP00000318355 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | 0.408 |
AQP4 | AQP3 | ENSP00000372654 | ENSP00000297991 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | aquaporin 3 (Gill blood group); Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct ce [...] | 0.412 |
AQP4 | AQP7 | ENSP00000372654 | ENSP00000297988 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | aquaporin 7; Forms a channel for water and glycerol | 0.423 |
AQP4 | AQP9 | ENSP00000372654 | ENSP00000219919 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | aquaporin 9; Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol | 0.402 |
AQP4 | GK5 | ENSP00000372654 | ENSP00000418001 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | glycerol kinase 5 (putative) | 0.779 |
AQP4 | GPD2 | ENSP00000372654 | ENSP00000308610 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.671 |
AQP5 | AQP10 | ENSP00000293599 | ENSP00000318355 | aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions | aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol | 0.876 |
AQP5 | GK5 | ENSP00000293599 | ENSP00000418001 | aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions | glycerol kinase 5 (putative) | 0.779 |
AQP5 | GPD2 | ENSP00000293599 | ENSP00000308610 | aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.671 |