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STRINGSTRING
GPX6 GPX6 SEPW1 SEPW1 SELK SELK SEP15 SEP15 MIEN1 MIEN1 VIMP VIMP SELO SELO SELT SELT C11orf31 C11orf31 SECISBP2 SECISBP2 EPT1 EPT1
"SELT" - selenoprotein T precursor in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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Experiments
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[Homology]
Score
SELTselenoprotein T precursor (195 aa)    
Predicted Functional Partners:
MIEN1
migration and invasion enhancer 1; Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process (115 aa)
            score_image   0.873
SEPW1
selenoprotein W, 1; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity) (88 aa)
            score_image   0.850
SELK
selenoprotein K (94 aa)
            score_image   0.844
SELO
selenoprotein O (669 aa)
            score_image   0.828
VIMP
VCP-interacting membrane protein; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination (189 aa)
            score_image   0.812
SEP15
15 kDa selenoprotein isoform 1 precursor ; May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity) (162 aa)
      score_image     score_image   0.763
C11orf31
chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential) (122 aa)
            score_image   0.753
SECISBP2
SECIS binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB (854 aa)
            score_image   0.709
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific); Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via ’Kennedy’ pathway (397 aa)
            score_image   0.659
GPX6
glutathione peroxidase 6 (olfactory) (221 aa)
            score_image   0.648
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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