SYNPR protein (Homo sapiens) - STRING network view

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SYNPR

synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity) (285 aa)

Predicted Functional Partners:

SYNGR1

0.872

SYNGR2

0.741

VAMP2

0.668

VAMP1

0.649

C3orf14

0.601

VAMP3

0.600

ENSG00000263620

0.583

SYT1

0.562

VAPA

0.510

SYN1

0.503

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3orf14	SYNPR	ENSP00000232519	ENSP00000418994	chromosome 3 open reading frame 14	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	0.601
ENSG00000263620	SYN1	ENSP00000464383	ENSP00000295987	Uncharacterized protein	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	0.677
ENSG00000263620	SYNPR	ENSP00000464383	ENSP00000418994	Uncharacterized protein	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	0.583
ENSG00000263620	SYT1	ENSP00000464383	ENSP00000261205	Uncharacterized protein	synaptotagmin I; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2	0.907
ENSG00000263620	VAPA	ENSP00000464383	ENSP00000345656	Uncharacterized protein	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; May play a role in vesicle trafficking	0.834
SYN1	ENSG00000263620	ENSP00000295987	ENSP00000464383	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	Uncharacterized protein	0.677
SYN1	SYNGR1	ENSP00000295987	ENSP00000332287	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	synaptogyrin 1; Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)	0.447
SYN1	SYNPR	ENSP00000295987	ENSP00000418994	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	0.503
SYN1	SYT1	ENSP00000295987	ENSP00000261205	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	synaptotagmin I; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2	0.834
SYN1	VAMP1	ENSP00000295987	ENSP00000379602	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	vesicle-associated membrane protein 1 (synaptobrevin 1); Involved in the targeting and/or fusion of transport vesicles to their target membrane	0.563
SYN1	VAMP2	ENSP00000295987	ENSP00000314214	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane	0.706
SYN1	VAMP3	ENSP00000295987	ENSP00000054666	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	vesicle-associated membrane protein 3; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	0.542
SYN1	VAPA	ENSP00000295987	ENSP00000345656	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; May play a role in vesicle trafficking	0.504
SYNGR1	SYN1	ENSP00000332287	ENSP00000295987	synaptogyrin 1; Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level	0.447
SYNGR1	SYNPR	ENSP00000332287	ENSP00000418994	synaptogyrin 1; Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	0.872
SYNGR1	SYT1	ENSP00000332287	ENSP00000261205	synaptogyrin 1; Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)	synaptotagmin I; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2	0.578
SYNGR2	SYNPR	ENSP00000225777	ENSP00000418994	synaptogyrin 2	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	0.741
SYNGR2	VAMP2	ENSP00000225777	ENSP00000314214	synaptogyrin 2	vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane	0.422
SYNPR	C3orf14	ENSP00000418994	ENSP00000232519	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	chromosome 3 open reading frame 14	0.601
SYNPR	ENSG00000263620	ENSP00000418994	ENSP00000464383	synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)	Uncharacterized protein	0.583

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