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STRINGSTRING
NOC2L NOC2L ENSG00000248354 ENSG00000248354 WDR36 WDR36 DIEXF DIEXF MPHOSPH10 MPHOSPH10 TBL3 TBL3 AATF AATF RRP9 RRP9 UTP3 UTP3 UTP6 UTP6 PWP2 PWP2
"DIEXF" - digestive organ expansion factor homolog in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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Predicted Interactions
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[Homology]
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DIEXFdigestive organ expansion factor homolog (zebrafish); Regulates the p53 pathway to control the expansion growth of digestive organs (By similarity) (756 aa)    
Predicted Functional Partners:
UTP3
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae); Essential for gene silencing- has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity) (479 aa)
      score_image score_image   score_image   0.991
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (681 aa)
      score_image score_image   score_image   0.964
TBL3
transducin (beta)-like 3 (808 aa)
      score_image     score_image   0.933
AATF
apoptosis antagonizing transcription factor; May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for th [...] (560 aa)
      score_image     score_image   0.921
WDR36
WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 (951 aa)
      score_image score_image   score_image   0.916
PWP2
PWP2 periodic tryptophan protein homolog (yeast) (919 aa)
      score_image     score_image   0.897
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (475 aa)
      score_image score_image   score_image   0.896
NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter (749 aa)
      score_image     score_image   0.894
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (597 aa)
      score_image     score_image   0.892
ENSG00000248354
Uncharacterized protein (205 aa)
      score_image     score_image   0.891
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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