Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
ACAA1 ACAA1 HLCS HLCS HADHB HADHB PCCB PCCB MCCC1 MCCC1 ACADM ACADM PCCA PCCA ACSS1 ACSS1 MUT MUT MCEE MCEE ACAA2 ACAA2
"PCCB" - propionyl CoA carboxylase, beta polypeptide in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCCBpropionyl CoA carboxylase, beta polypeptide (559 aa)    
Predicted Functional Partners:
PCCA
propionyl CoA carboxylase, alpha polypeptide (728 aa)
score_image score_image   score_image score_image score_image score_image   0.999
MCEE
methylmalonyl CoA epimerase (176 aa)
score_image     score_image   score_image score_image   0.977
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase (726 aa)
score_image         score_image score_image   0.964
MUT
methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species (750 aa)
score_image   score_image       score_image   0.963
ACSS1
acyl-CoA synthetase short-chain family member 1 (689 aa)
      score_image score_image score_image score_image   0.952
ACAA2
acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage (397 aa)
score_image       score_image score_image score_image   0.951
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha) (725 aa)
score_image score_image   score_image score_image   score_image   0.949
ACADM
acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 (425 aa)
score_image     score_image   score_image score_image   0.941
ACAA1
acetyl-CoA acyltransferase 1 (424 aa)
score_image       score_image score_image score_image   0.939
HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (474 aa)
score_image       score_image score_image score_image   0.936
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (40%)