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STRINGSTRING
CRISP2 CRISP2 MTERFD2 MTERFD2 NSUN4 NSUN4 NOP56 NOP56 ENSG00000204775 ENSG00000204775 NSUN5 NSUN5 NOP58 NOP58 TRMT1 TRMT1 DDX24 DDX24 METTL1 METTL1 BOP1 BOP1
"NSUN4" - NOP2/Sun domain family, member 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSUN4NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis (384 aa)    
Predicted Functional Partners:
MTERFD2
MTERF domain containing 2; Required for the targeting of the methyltransferase NSUN4 to mitochondrial large ribosomal subunit and efficient rRNA methylation (381 aa)
        score_image   score_image   0.997
CRISP2
cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation (By similarity) (243 aa)
            score_image   0.889
NSUN5
NOP2/Sun domain family, member 5 (470 aa)
    score_image score_image     score_image   0.852
METTL1
methyltransferase like 1; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (276 aa)
      score_image score_image   score_image   0.851
DDX24
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24; ATP-dependent RNA helicase (Potential) (859 aa)
      score_image score_image   score_image   0.815
ENSG00000204775
KM-PA-2 protein; Uncharacterized protein (634 aa)
      score_image score_image   score_image   0.784
BOP1
block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (746 aa)
      score_image score_image   score_image   0.784
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae); Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (659 aa)
      score_image score_image   score_image   0.735
NOP56
NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis (594 aa)
      score_image score_image   score_image   0.734
NOP58
NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity) (529 aa)
      score_image score_image   score_image   0.734
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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