Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | RPL41 | ribosomal protein L41 (25 aa) | ||||||||||||
Predicted Functional Partners:
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 | RPL37A | ribosomal protein L37a (92 aa) |
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0.949 | |||||||||
 | RPS29 | ribosomal protein S29 (67 aa) |
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0.948 | |||||||||
 | RPL38 | ribosomal protein L38 (70 aa) |
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0.948 | |||||||||
 | RPL29 | ribosomal protein L29 (159 aa) |
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0.948 | |||||||||
 | RPL37 | ribosomal protein L37; Binds to the 23S rRNA (By similarity) (97 aa) |
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0.945 | |||||||||
 | RPL35 | ribosomal protein L35 (123 aa) |
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0.945 | |||||||||
 | RPL24 | ribosomal protein L24 (157 aa) |
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0.940 | |||||||||
 | RPL39 | ribosomal protein L39 (51 aa) |
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0.939 | |||||||||
 | RPL23 | ribosomal protein L23 (140 aa) |
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0.939 | |||||||||
 | RPL3 | ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes (403 aa) |
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0.939 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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