HMGXB3 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HMGXB3

HMG box domain containing 3 (1292 aa)

Predicted Functional Partners:

TIGD6

0.607

COL9A2

0.563

ZNF480

0.533

GBA3

0.504

TIGD4

0.483

KLRP

0.472

ZZEF1

0.472

CDH9

0.412

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH9	GBA3	ENSP00000231021	ENSP00000471397	cadherin 9, type 2 (T1-cadherin); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	Cytosolic beta-glucosidase ; Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide	0.435
CDH9	HMGXB3	ENSP00000231021	ENSP00000421917	cadherin 9, type 2 (T1-cadherin); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	HMG box domain containing 3	0.412
CDH9	ZZEF1	ENSP00000231021	ENSP00000371051	cadherin 9, type 2 (T1-cadherin); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	zinc finger, ZZ-type with EF-hand domain 1	0.405
COL9A2	HMGXB3	ENSP00000361834	ENSP00000421917	collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye	HMG box domain containing 3	0.563
GBA3	CDH9	ENSP00000471397	ENSP00000231021	Cytosolic beta-glucosidase ; Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide	cadherin 9, type 2 (T1-cadherin); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	0.435
GBA3	HMGXB3	ENSP00000471397	ENSP00000421917	Cytosolic beta-glucosidase ; Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide	HMG box domain containing 3	0.504
GBA3	ZNF480	ENSP00000471397	ENSP00000417424	Cytosolic beta-glucosidase ; Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide	zinc finger protein 480; Involved in transcriptional regulation as an activator	0.471
GBA3	ZZEF1	ENSP00000471397	ENSP00000371051	Cytosolic beta-glucosidase ; Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide	zinc finger, ZZ-type with EF-hand domain 1	0.458
HMGXB3	CDH9	ENSP00000421917	ENSP00000231021	HMG box domain containing 3	cadherin 9, type 2 (T1-cadherin); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types	0.412
HMGXB3	COL9A2	ENSP00000421917	ENSP00000361834	HMG box domain containing 3	collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye	0.563
HMGXB3	GBA3	ENSP00000421917	ENSP00000471397	HMG box domain containing 3	Cytosolic beta-glucosidase ; Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide	0.504
HMGXB3	KLRP	ENSP00000421917	ENSP00000471024	HMG box domain containing 3	glucosidase, beta, acid 3 (cytosolic) (EC-3.2.1.21)	0.472
HMGXB3	TIGD4	ENSP00000421917	ENSP00000355162	HMG box domain containing 3	tigger transposable element derived 4	0.483
HMGXB3	TIGD6	ENSP00000421917	ENSP00000296736	HMG box domain containing 3	tigger transposable element derived 6	0.607
HMGXB3	ZNF480	ENSP00000421917	ENSP00000417424	HMG box domain containing 3	zinc finger protein 480; Involved in transcriptional regulation as an activator	0.533
HMGXB3	ZZEF1	ENSP00000421917	ENSP00000371051	HMG box domain containing 3	zinc finger, ZZ-type with EF-hand domain 1	0.472
KLRP	HMGXB3	ENSP00000471024	ENSP00000421917	glucosidase, beta, acid 3 (cytosolic) (EC-3.2.1.21)	HMG box domain containing 3	0.472
KLRP	ZNF480	ENSP00000471024	ENSP00000417424	glucosidase, beta, acid 3 (cytosolic) (EC-3.2.1.21)	zinc finger protein 480; Involved in transcriptional regulation as an activator	0.424
TIGD4	HMGXB3	ENSP00000355162	ENSP00000421917	tigger transposable element derived 4	HMG box domain containing 3	0.483
TIGD6	HMGXB3	ENSP00000296736	ENSP00000421917	tigger transposable element derived 6	HMG box domain containing 3	0.607

page 1 of 2

Textmining

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About