OCIAD2 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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Score

OCIAD2

OCIA domain containing 2 (154 aa)

Predicted Functional Partners:

NCSTN

0.807

ILF3

0.644

MMGT1

0.644

UBC

0.620

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ILF3	OCIAD2	ENSP00000404121	ENSP00000423014	interleukin enhancer binding factor 3, 90kDa	OCIA domain containing 2	0.644
ILF3	UBC	ENSP00000404121	ENSP00000344818	interleukin enhancer binding factor 3, 90kDa	ubiquitin C	0.969
MMGT1	OCIAD2	ENSP00000306220	ENSP00000423014	membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity)	OCIA domain containing 2	0.644
MMGT1	UBC	ENSP00000306220	ENSP00000344818	membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity)	ubiquitin C	0.632
NCSTN	OCIAD2	ENSP00000294785	ENSP00000423014	nicastrin; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex	OCIA domain containing 2	0.807
NCSTN	UBC	ENSP00000294785	ENSP00000344818	nicastrin; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex	ubiquitin C	0.979
OCIAD2	ILF3	ENSP00000423014	ENSP00000404121	OCIA domain containing 2	interleukin enhancer binding factor 3, 90kDa	0.644
OCIAD2	MMGT1	ENSP00000423014	ENSP00000306220	OCIA domain containing 2	membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity)	0.644
OCIAD2	NCSTN	ENSP00000423014	ENSP00000294785	OCIA domain containing 2	nicastrin; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex	0.807
OCIAD2	UBC	ENSP00000423014	ENSP00000344818	OCIA domain containing 2	ubiquitin C	0.620
UBC	ILF3	ENSP00000344818	ENSP00000404121	ubiquitin C	interleukin enhancer binding factor 3, 90kDa	0.969
UBC	MMGT1	ENSP00000344818	ENSP00000306220	ubiquitin C	membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity)	0.632
UBC	NCSTN	ENSP00000344818	ENSP00000294785	ubiquitin C	nicastrin; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex	0.979
UBC	OCIAD2	ENSP00000344818	ENSP00000423014	ubiquitin C	OCIA domain containing 2	0.620

Experiments

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Textmining

Fusion

Coexpression

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