KCTD16 protein (Homo sapiens) - STRING network view

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KCTD16

potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) (428 aa)

Predicted Functional Partners:

KCTD19

0.592

KCND2

0.591

KCND3

0.591

HMHB1

0.586

ZNF229

0.548

ZNF724P

0.503

UBC

0.499

ARHGAP26

0.492

KCTD20

0.487

OR1B1

0.416

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP26	KCTD16	ENSP00000274498	ENSP00000424151	Rho GTPase activating protein 26; GTPase-activating protein for RHOA and CDC42	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	0.492
ARHGAP26	UBC	ENSP00000274498	ENSP00000344818	Rho GTPase activating protein 26; GTPase-activating protein for RHOA and CDC42	ubiquitin C	0.721
HMHB1	KCTD16	ENSP00000289448	ENSP00000424151	histocompatibility (minor) HB-1; Precursor of the histocomplatibility antigen HB-1. More generally, minor histocomplatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-ho [...]	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	0.586
KCND2	KCND3	ENSP00000333496	ENSP00000319591	potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	potassium voltage-gated channel, Shal-related subfamily, member 3; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	0.901
KCND2	KCTD16	ENSP00000333496	ENSP00000424151	potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	0.591
KCND3	KCND2	ENSP00000319591	ENSP00000333496	potassium voltage-gated channel, Shal-related subfamily, member 3; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	0.901
KCND3	KCTD16	ENSP00000319591	ENSP00000424151	potassium voltage-gated channel, Shal-related subfamily, member 3; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	0.591
KCTD16	ARHGAP26	ENSP00000424151	ENSP00000274498	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	Rho GTPase activating protein 26; GTPase-activating protein for RHOA and CDC42	0.492
KCTD16	HMHB1	ENSP00000424151	ENSP00000289448	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	histocompatibility (minor) HB-1; Precursor of the histocomplatibility antigen HB-1. More generally, minor histocomplatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-ho [...]	0.586
KCTD16	KCND2	ENSP00000424151	ENSP00000333496	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	0.591
KCTD16	KCND3	ENSP00000424151	ENSP00000319591	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	potassium voltage-gated channel, Shal-related subfamily, member 3; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits	0.591
KCTD16	KCTD19	ENSP00000424151	ENSP00000305702	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	potassium channel tetramerisation domain containing 19	0.592
KCTD16	KCTD20	ENSP00000424151	ENSP00000362836	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	potassium channel tetramerisation domain containing 20	0.487
KCTD16	OR1B1	ENSP00000424151	ENSP00000303151	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	olfactory receptor, family 1, subfamily B, member 1; Odorant receptor (Potential)	0.416
KCTD16	UBC	ENSP00000424151	ENSP00000344818	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	ubiquitin C	0.499
KCTD16	ZNF229	ENSP00000424151	ENSP00000466519	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	zinc finger protein 229; May be involved in transcriptional regulation	0.548
KCTD16	ZNF724P	ENSP00000424151	ENSP00000413411	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	zinc finger protein 724, pseudogene; May be involved in transcriptional regulation (By similarity)	0.503
KCTD19	KCTD16	ENSP00000305702	ENSP00000424151	potassium channel tetramerisation domain containing 19	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	0.592
KCTD20	KCTD16	ENSP00000362836	ENSP00000424151	potassium channel tetramerisation domain containing 20	potassium channel tetramerisation domain containing 16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity)	0.487
KCTD20	UBC	ENSP00000362836	ENSP00000344818	potassium channel tetramerisation domain containing 20	ubiquitin C	0.854

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