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CCDC158 CCDC158 AMOT AMOT MYRIP MYRIP TPM3 TPM3 C1orf216 C1orf216 USHBP1 USHBP1 KRT15 KRT15 CCDC64B CCDC64B OR51Q1 OR51Q1 KANSL1L KANSL1L TRIM61 TRIM61
"C1orf216" - chromosome 1 open reading frame 216 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1orf216chromosome 1 open reading frame 216 (229 aa)    
Predicted Functional Partners:
OR51Q1
olfactory receptor, family 51, subfamily Q, member 1; Odorant receptor (Potential) (317 aa)
            score_image   0.700
KANSL1L
KAT8 regulatory NSL complex subunit 1-like (987 aa)
            score_image   0.644
TPM3
tropomyosin 3; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (285 aa)
        score_image       0.642
KRT15
keratin 15 (456 aa)
        score_image       0.595
AMOT
angiomotin; Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions (1084 aa)
        score_image       0.589
CCDC64B
coiled-coil domain containing 64B (508 aa)
            score_image   0.570
TRIM61
tripartite motif containing 61 (209 aa)
            score_image   0.532
USHBP1
Usher syndrome 1C binding protein 1 (703 aa)
        score_image       0.528
CCDC158
coiled-coil domain containing 158 (1113 aa)
        score_image       0.524
MYRIP
myosin VIIA and Rab interacting protein (859 aa)
        score_image       0.524
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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