PGM3 protein (Homo sapiens) - STRING network view

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PGM3

phosphoglucomutase 3 (570 aa)

Predicted Functional Partners:

UAP1

0.978

GNPNAT1

0.975

UAP1L1

0.960

WRNIP1

0.945

NAGK

0.942

ATP6C

0.902

UBC

0.891

PGM2

0.822

PGM1

0.810

SPRTN

0.767

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6C	NAGK	ENSP00000455561	ENSP00000389087	Uncharacterized protein	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	0.948
ATP6C	PGM3	ENSP00000455561	ENSP00000425809	Uncharacterized protein	phosphoglucomutase 3	0.902
GNPNAT1	NAGK	ENSP00000216410	ENSP00000389087	glucosamine-phosphate N-acetyltransferase 1	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	0.936
GNPNAT1	PGM2	ENSP00000216410	ENSP00000371393	glucosamine-phosphate N-acetyltransferase 1	phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity	0.421
GNPNAT1	PGM3	ENSP00000216410	ENSP00000425809	glucosamine-phosphate N-acetyltransferase 1	phosphoglucomutase 3	0.975
GNPNAT1	UAP1	ENSP00000216410	ENSP00000356903	glucosamine-phosphate N-acetyltransferase 1	UDP-N-acteylglucosamine pyrophosphorylase 1; Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P	0.774
GNPNAT1	UAP1L1	ENSP00000216410	ENSP00000386935	glucosamine-phosphate N-acetyltransferase 1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.531
GNPNAT1	UBC	ENSP00000216410	ENSP00000344818	glucosamine-phosphate N-acetyltransferase 1	ubiquitin C	0.747
NAGK	ATP6C	ENSP00000389087	ENSP00000455561	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	Uncharacterized protein	0.948
NAGK	GNPNAT1	ENSP00000389087	ENSP00000216410	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	glucosamine-phosphate N-acetyltransferase 1	0.936
NAGK	PGM3	ENSP00000389087	ENSP00000425809	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	phosphoglucomutase 3	0.942
NAGK	UAP1	ENSP00000389087	ENSP00000356903	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	UDP-N-acteylglucosamine pyrophosphorylase 1; Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P	0.424
NAGK	UBC	ENSP00000389087	ENSP00000344818	N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity	ubiquitin C	0.486
PGM1	PGM2	ENSP00000360124	ENSP00000371393	phosphoglucomutase 1	phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity	0.993
PGM1	PGM3	ENSP00000360124	ENSP00000425809	phosphoglucomutase 1	phosphoglucomutase 3	0.810
PGM1	UBC	ENSP00000360124	ENSP00000344818	phosphoglucomutase 1	ubiquitin C	0.924
PGM2	GNPNAT1	ENSP00000371393	ENSP00000216410	phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity	glucosamine-phosphate N-acetyltransferase 1	0.421
PGM2	PGM1	ENSP00000371393	ENSP00000360124	phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity	phosphoglucomutase 1	0.993
PGM2	PGM3	ENSP00000371393	ENSP00000425809	phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity	phosphoglucomutase 3	0.822
PGM2	UAP1	ENSP00000371393	ENSP00000356903	phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity	UDP-N-acteylglucosamine pyrophosphorylase 1; Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P	0.456

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