node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AK4 | ECH1 | ENSP00000322175 | ENSP00000221418 | adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor | enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) | 0.629 |
AK4 | IGBP1 | ENSP00000322175 | ENSP00000348784 | adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor | immunoglobulin (CD79A) binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits | 0.509 |
AK4 | RAI14 | ENSP00000322175 | ENSP00000427123 | adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor | retinoic acid induced 14 | 0.610 |
AK4 | UBC | ENSP00000322175 | ENSP00000344818 | adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor | ubiquitin C | 0.465 |
CDK14 | RAI14 | ENSP00000265741 | ENSP00000427123 | cyclin-dependent kinase 14 | retinoic acid induced 14 | 0.569 |
CDK15 | RAI14 | ENSP00000260967 | ENSP00000427123 | cyclin-dependent kinase 15 | retinoic acid induced 14 | 0.541 |
ECH1 | AK4 | ENSP00000221418 | ENSP00000322175 | enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) | adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor | 0.629 |
ECH1 | IGBP1 | ENSP00000221418 | ENSP00000348784 | enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) | immunoglobulin (CD79A) binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits | 0.527 |
ECH1 | RAI14 | ENSP00000221418 | ENSP00000427123 | enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) | retinoic acid induced 14 | 0.588 |
ECH1 | UBC | ENSP00000221418 | ENSP00000344818 | enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) | ubiquitin C | 0.721 |
FEZ2 | RAI14 | ENSP00000368547 | ENSP00000427123 | fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) | retinoic acid induced 14 | 0.479 |
FEZ2 | UBC | ENSP00000368547 | ENSP00000344818 | fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) | ubiquitin C | 0.483 |
IGBP1 | AK4 | ENSP00000348784 | ENSP00000322175 | immunoglobulin (CD79A) binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits | adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor | 0.509 |
IGBP1 | ECH1 | ENSP00000348784 | ENSP00000221418 | immunoglobulin (CD79A) binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits | enoyl CoA hydratase 1, peroxisomal; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA (By similarity) | 0.527 |
IGBP1 | RAI14 | ENSP00000348784 | ENSP00000427123 | immunoglobulin (CD79A) binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits | retinoic acid induced 14 | 0.574 |
IGBP1 | UBC | ENSP00000348784 | ENSP00000344818 | immunoglobulin (CD79A) binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits | ubiquitin C | 0.963 |
KLF15 | RAI14 | ENSP00000296233 | ENSP00000427123 | Kruppel-like factor 15; Transcriptional activator. Binds to the GA element of the CLCNKA promoter | retinoic acid induced 14 | 0.461 |
NEK2 | RAI14 | ENSP00000355966 | ENSP00000427123 | NIMA-related kinase 2; Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. Regulates centrosome separation (essential for the formation of bipolar spindles and high-fidelity chromosome separation) by phosphorylating centrosomal proteins such as CROCC, CEP250 and NINL, resulting in their displacement from the centrosomes. Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80. Involved in regulation of mitotic checkpoint protein complex [...] | retinoic acid induced 14 | 0.602 |
NEK2 | UBC | ENSP00000355966 | ENSP00000344818 | NIMA-related kinase 2; Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. Regulates centrosome separation (essential for the formation of bipolar spindles and high-fidelity chromosome separation) by phosphorylating centrosomal proteins such as CROCC, CEP250 and NINL, resulting in their displacement from the centrosomes. Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80. Involved in regulation of mitotic checkpoint protein complex [...] | ubiquitin C | 0.986 |
PTPN14 | RAI14 | ENSP00000355923 | ENSP00000427123 | protein tyrosine phosphatase, non-receptor type 14; Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor | retinoic acid induced 14 | 0.462 |