UTP14C protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

UTP14C

UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast); Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity) (766 aa)

Predicted Functional Partners:

DHX37

0.988

RBM28

0.988

TBL3

0.985

FTSJ3

0.983

NOL10

0.982

DDX27

0.979

EBNA1BP2

0.976

MPHOSPH10

0.975

NOP14

0.964

CIRH1A

0.957

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIRH1A	DDX27	ENSP00000327179	ENSP00000360828	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	0.931
CIRH1A	DHX37	ENSP00000327179	ENSP00000311135	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.951
CIRH1A	EBNA1BP2	ENSP00000327179	ENSP00000407323	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	0.721
CIRH1A	FTSJ3	ENSP00000327179	ENSP00000396673	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation	0.898
CIRH1A	MPHOSPH10	ENSP00000327179	ENSP00000244230	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	0.985
CIRH1A	NOL10	ENSP00000327179	ENSP00000371101	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	nucleolar protein 10	0.974
CIRH1A	NOP14	ENSP00000327179	ENSP00000315674	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.991
CIRH1A	RBM28	ENSP00000327179	ENSP00000223073	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes	0.941
CIRH1A	TBL3	ENSP00000327179	ENSP00000454836	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	transducin (beta)-like 3	0.985
CIRH1A	UTP14C	ENSP00000327179	ENSP00000428619	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast); Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity)	0.957
DDX27	CIRH1A	ENSP00000360828	ENSP00000327179	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV	0.931
DDX27	DHX37	ENSP00000360828	ENSP00000311135	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.874
DDX27	EBNA1BP2	ENSP00000360828	ENSP00000407323	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	0.972
DDX27	FTSJ3	ENSP00000360828	ENSP00000396673	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation	0.991
DDX27	MPHOSPH10	ENSP00000360828	ENSP00000244230	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	0.923
DDX27	NOL10	ENSP00000360828	ENSP00000371101	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	nucleolar protein 10	0.938
DDX27	NOP14	ENSP00000360828	ENSP00000315674	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.931
DDX27	RBM28	ENSP00000360828	ENSP00000223073	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes	0.995
DDX27	TBL3	ENSP00000360828	ENSP00000454836	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	transducin (beta)-like 3	0.892
DDX27	UTP14C	ENSP00000360828	ENSP00000428619	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast); Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity)	0.979

page 1 of 6

Experiments

Cooccurrence

Textmining

Neighborhood

Coexpression

Fusion

Databases

© STRING Consortium 2017

Credits

Access

Info

About