Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | ENSG00000259024 | FAM18B2-CDRT4 readthrough (164 aa) | ||||||||||||
Predicted Functional Partners:
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 | YIPF6 | Yip1 domain family, member 6 (236 aa) |
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0.812 | ||||||||
 | YIPF2 | Yip1 domain family, member 2 (316 aa) |
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0.650 | ||||||||
 | SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3; Uridine diphosphate-N-acetylglucosamine transporter in the Golgi apparatus (325 aa) |
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0.525 | ||||||||||
 | COG1 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) (980 aa) |
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0.521 | ||||||||||
 | TMEM64 | transmembrane protein 64 (380 aa) |
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0.491 | ||||||||||
 | TMEM41A | transmembrane protein 41A (264 aa) |
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0.491 | ||||||||||
 | TMEM41B | transmembrane protein 41B (291 aa) |
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0.491 | ||||||||||
 | GMFG | glia maturation factor, gamma (142 aa) |
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0.482 | ||||||||||
 | GMFB | glia maturation factor, beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells (142 aa) |
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0.482 | ||||||||||
 | UROD | uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (367 aa) |
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0.463 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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