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GYG1 GYG1 RFT1 RFT1 CANX CANX ALG11 ALG11 ALG3 ALG3 PMM2 PMM2 ALG2 ALG2 ALG1 ALG1 ALG14 ALG14 ALG1L ALG1L GNE GNE
"ALG11" - asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog in Homo sapiens
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Predicted Interactions
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ALG11asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast); Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain (492 aa)    
Predicted Functional Partners:
ALG3
asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae); Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol (438 aa)
        score_image score_image score_image   0.974
RFT1
RFT1 homolog (S. cerevisiae); May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane (541 aa)
        score_image score_image score_image   0.962
ALG2
asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate (416 aa)
        score_image score_image score_image score_image 0.945
PMM2
phosphomannomutase 2; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions (By similarity) (246 aa)
            score_image   0.789
ALG1
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (464 aa)
      score_image score_image   score_image   0.767
GYG1
glycogenin 1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase (350 aa)
        score_image   score_image   0.713
ALG1L
asparagine-linked glycosylation 1-like; Putative glycosyltransferase (By similarity) (187 aa)
      score_image score_image   score_image   0.685
CANX
calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at [...] (592 aa)
      score_image     score_image   0.681
ALG14
asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER (216 aa)
      score_image     score_image   0.669
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (753 aa)
score_image     score_image     score_image   0.621
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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