EIF5AL1 protein (Homo sapiens) - STRING network view

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EIF5AL1

eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...] (154 aa)

Predicted Functional Partners:

RPL15

0.975

UBC

0.955

RPL38

0.936

RPS23

0.821

RPS2

0.820

MRPS5

0.820

DHPS

0.808

RPLP2

0.807

RPS13

0.798

RPS15

0.796

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHPS	EIF5AL1	ENSP00000210060	ENSP00000430706	deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	0.808
DHPS	UBC	ENSP00000210060	ENSP00000344818	deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	ubiquitin C	0.866
EIF5AL1	DHPS	ENSP00000430706	ENSP00000210060	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	0.808
EIF5AL1	MRPS5	ENSP00000430706	ENSP00000272418	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	mitochondrial ribosomal protein S5	0.820
EIF5AL1	RPL15	ENSP00000430706	ENSP00000309334	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein L15	0.975
EIF5AL1	RPL38	ENSP00000430706	ENSP00000309830	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein L38	0.936
EIF5AL1	RPLP2	ENSP00000430706	ENSP00000322419	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein, large, P2; Plays an important role in the elongation step of protein synthesis	0.807
EIF5AL1	RPS13	ENSP00000430706	ENSP00000435777	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein S13	0.798
EIF5AL1	RPS15	ENSP00000430706	ENSP00000467676	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein S15	0.796
EIF5AL1	RPS2	ENSP00000430706	ENSP00000341885	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein S2	0.820
EIF5AL1	RPS23	ENSP00000430706	ENSP00000296674	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ribosomal protein S23	0.821
EIF5AL1	UBC	ENSP00000430706	ENSP00000344818	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	ubiquitin C	0.955
MRPS5	EIF5AL1	ENSP00000272418	ENSP00000430706	mitochondrial ribosomal protein S5	eukaryotic translation initiation factor 5A-like 1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...]	0.820
MRPS5	RPL15	ENSP00000272418	ENSP00000309334	mitochondrial ribosomal protein S5	ribosomal protein L15	0.890
MRPS5	RPL38	ENSP00000272418	ENSP00000309830	mitochondrial ribosomal protein S5	ribosomal protein L38	0.899
MRPS5	RPLP2	ENSP00000272418	ENSP00000322419	mitochondrial ribosomal protein S5	ribosomal protein, large, P2; Plays an important role in the elongation step of protein synthesis	0.547
MRPS5	RPS13	ENSP00000272418	ENSP00000435777	mitochondrial ribosomal protein S5	ribosomal protein S13	0.924
MRPS5	RPS15	ENSP00000272418	ENSP00000467676	mitochondrial ribosomal protein S5	ribosomal protein S15	0.996
MRPS5	RPS23	ENSP00000272418	ENSP00000296674	mitochondrial ribosomal protein S5	ribosomal protein S23	0.988
MRPS5	UBC	ENSP00000272418	ENSP00000344818	mitochondrial ribosomal protein S5	ubiquitin C	0.761

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