node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGR2 | GDAP1 | ENSP00000242480 | ENSP00000220822 | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | 0.566 |
EGR2 | GJB1 | ENSP00000242480 | ENSP00000354900 | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.681 |
EGR2 | MED25 | ENSP00000242480 | ENSP00000326767 | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | mediator complex subunit 25 | 0.900 |
EGR2 | MPZ | ENSP00000242480 | ENSP00000431538 | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | myelin protein zero; Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae | 0.720 |
EGR2 | MTMR2 | ENSP00000242480 | ENSP00000345752 | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | myotubularin related protein 2; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate | 0.504 |
EGR2 | PMP22 | ENSP00000242480 | ENSP00000308937 | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system | 0.912 |
GDAP1 | EGR2 | ENSP00000220822 | ENSP00000242480 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | 0.566 |
GDAP1 | GJB1 | ENSP00000220822 | ENSP00000354900 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.725 |
GDAP1 | KIF1B | ENSP00000220822 | ENSP00000263934 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | kinesin family member 1B | 0.747 |
GDAP1 | MED25 | ENSP00000220822 | ENSP00000326767 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | mediator complex subunit 25 | 0.681 |
GDAP1 | MFN2 | ENSP00000220822 | ENSP00000235329 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | mitofusin 2; Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation | 0.746 |
GDAP1 | MPZ | ENSP00000220822 | ENSP00000431538 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | myelin protein zero; Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae | 0.870 |
GDAP1 | MTMR2 | ENSP00000220822 | ENSP00000345752 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | myotubularin related protein 2; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate | 0.725 |
GDAP1 | PES1 | ENSP00000220822 | ENSP00000346725 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.560 |
GDAP1 | PMP22 | ENSP00000220822 | ENSP00000308937 | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system | 0.749 |
GJB1 | EGR2 | ENSP00000354900 | ENSP00000242480 | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4 | 0.681 |
GJB1 | GDAP1 | ENSP00000354900 | ENSP00000220822 | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | ganglioside induced differentiation associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission | 0.725 |
GJB1 | KIF1B | ENSP00000354900 | ENSP00000263934 | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | kinesin family member 1B | 0.504 |
GJB1 | MED25 | ENSP00000354900 | ENSP00000326767 | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | mediator complex subunit 25 | 0.607 |
GJB1 | MFN2 | ENSP00000354900 | ENSP00000235329 | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | mitofusin 2; Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation | 0.632 |