| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKAP1 | AKAP3 | ENSP00000337736 | ENSP00000228850 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | 0.608 |
| AKAP1 | CABYR | ENSP00000337736 | ENSP00000432870 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | 0.608 |
| AKAP1 | PRKAR2A | ENSP00000337736 | ENSP00000265563 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.999 |
| AKAP3 | AKAP1 | ENSP00000228850 | ENSP00000337736 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | 0.608 |
| AKAP3 | CABYR | ENSP00000228850 | ENSP00000432870 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | 0.970 |
| AKAP3 | CCDC54 | ENSP00000228850 | ENSP00000261058 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | coiled-coil domain containing 54 | 0.913 |
| AKAP3 | FSCB | ENSP00000228850 | ENSP00000344579 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | fibrous sheath CABYR binding protein; May be involved in the later stages of fibrous sheath biogenesis. Binds calcium (By similarity) | 0.406 |
| AKAP3 | PRKAR2A | ENSP00000228850 | ENSP00000265563 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.918 |
| AKAP3 | ROPN1 | ENSP00000228850 | ENSP00000184183 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | rhophilin associated tail protein 1 | 0.937 |
| AKAP3 | ROPN1L | ENSP00000228850 | ENSP00000274134 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | rhophilin associated tail protein 1-like | 0.936 |
| CABYR | AKAP1 | ENSP00000432870 | ENSP00000337736 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | 0.608 |
| CABYR | AKAP3 | ENSP00000432870 | ENSP00000228850 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | 0.970 |
| CABYR | CCDC54 | ENSP00000432870 | ENSP00000261058 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | coiled-coil domain containing 54 | 0.581 |
| CABYR | FSCB | ENSP00000432870 | ENSP00000344579 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | fibrous sheath CABYR binding protein; May be involved in the later stages of fibrous sheath biogenesis. Binds calcium (By similarity) | 0.974 |
| CABYR | GSK3B | ENSP00000432870 | ENSP00000324806 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | glycogen synthase kinase 3 beta; Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glyc [...] | 0.695 |
| CABYR | PRKAR2A | ENSP00000432870 | ENSP00000265563 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.746 |
| CABYR | ROPN1 | ENSP00000432870 | ENSP00000184183 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | rhophilin associated tail protein 1 | 0.866 |
| CABYR | ROPN1L | ENSP00000432870 | ENSP00000274134 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | rhophilin associated tail protein 1-like | 0.864 |
| CCDC54 | AKAP3 | ENSP00000261058 | ENSP00000228850 | coiled-coil domain containing 54 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | 0.913 |
| CCDC54 | CABYR | ENSP00000261058 | ENSP00000432870 | coiled-coil domain containing 54 | calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium | 0.581 |
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