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KCNAB3 KCNAB3 KCNAB1 KCNAB1 KCNQ2 KCNQ2 KCNAB2 KCNAB2 KCNQ3 KCNQ3 KCNC3 KCNC3 KCNH1 KCNH1 KCNH2 KCNH2 KCND2 KCND2 KCNH8 KCNH8 KCNH5 KCNH5
"KCNC3" - potassium voltage-gated channel, Shaw-related subfamily, member 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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KCNC3potassium voltage-gated channel, Shaw-related subfamily, member 3; This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (757 aa)    
Predicted Functional Partners:
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1 (419 aa)
          score_image score_image   0.944
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5 (404 aa)
          score_image score_image   0.944
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2 (415 aa)
          score_image score_image   0.943
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1 (1159 aa)
        score_image score_image score_image   0.936
KCNH5
potassium voltage-gated channel, subfamily H (eag-related), member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly (988 aa)
        score_image score_image score_image   0.928
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly (1107 aa)
        score_image score_image score_image   0.926
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1; Pore-forming (alpha) subunit of voltage-gated non- inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts (989 aa)
        score_image score_image score_image   0.924
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits (630 aa)
          score_image score_image score_image 0.924
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3; Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs (872 aa)
          score_image score_image score_image 0.924
KCNQ2
potassium voltage-gated channel, KQT-like subfamily, member 2 (872 aa)
          score_image score_image score_image 0.924
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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