TMPRSS13 protein (Homo sapiens) - STRING network view

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TMPRSS13

transmembrane protease, serine 13 (567 aa)

Predicted Functional Partners:

AIRE

0.543

CYP1A1

0.508

SLC6A8

0.483

SERPINA1

0.458

TRPV4

0.457

PRDM10

0.457

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIRE	TMPRSS13	ENSP00000291582	ENSP00000434279	autoimmune regulator; Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5’-. ATTGGTTA-3’ combined with a 5’-TTATTA-3’ box. Binds to nucleosomes (By similarity). Binds to chromatin and interacts selectively with histone H3 that is not methylated at ’Lys-4’, not phosphorylated at ’Thr-3’ and not methylated at ’Arg-2’. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene expression. Functions as a trans [...]	transmembrane protease, serine 13	0.543
CYP1A1	PRDM10	ENSP00000369050	ENSP00000351686	cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics	PR domain containing 10	0.521
CYP1A1	TMPRSS13	ENSP00000369050	ENSP00000434279	cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics	transmembrane protease, serine 13	0.508
PRDM10	CYP1A1	ENSP00000351686	ENSP00000369050	PR domain containing 10	cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics	0.521
PRDM10	SERPINA1	ENSP00000351686	ENSP00000348068	PR domain containing 10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.508
PRDM10	TMPRSS13	ENSP00000351686	ENSP00000434279	PR domain containing 10	transmembrane protease, serine 13	0.457
PRDM10	TRPV4	ENSP00000351686	ENSP00000261740	PR domain containing 10	transient receptor potential cation channel, subfamily V, member 4	0.584
SERPINA1	PRDM10	ENSP00000348068	ENSP00000351686	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	PR domain containing 10	0.508
SERPINA1	TMPRSS13	ENSP00000348068	ENSP00000434279	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	transmembrane protease, serine 13	0.458
SLC6A8	TMPRSS13	ENSP00000253122	ENSP00000434279	solute carrier family 6 (neurotransmitter transporter, creatine), member 8; Required for the uptake of creatine in muscles and brain	transmembrane protease, serine 13	0.483
TMPRSS13	AIRE	ENSP00000434279	ENSP00000291582	transmembrane protease, serine 13	autoimmune regulator; Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5’-. ATTGGTTA-3’ combined with a 5’-TTATTA-3’ box. Binds to nucleosomes (By similarity). Binds to chromatin and interacts selectively with histone H3 that is not methylated at ’Lys-4’, not phosphorylated at ’Thr-3’ and not methylated at ’Arg-2’. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene expression. Functions as a trans [...]	0.543
TMPRSS13	CYP1A1	ENSP00000434279	ENSP00000369050	transmembrane protease, serine 13	cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics	0.508
TMPRSS13	PRDM10	ENSP00000434279	ENSP00000351686	transmembrane protease, serine 13	PR domain containing 10	0.457
TMPRSS13	SERPINA1	ENSP00000434279	ENSP00000348068	transmembrane protease, serine 13	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.458
TMPRSS13	SLC6A8	ENSP00000434279	ENSP00000253122	transmembrane protease, serine 13	solute carrier family 6 (neurotransmitter transporter, creatine), member 8; Required for the uptake of creatine in muscles and brain	0.483
TMPRSS13	TRPV4	ENSP00000434279	ENSP00000261740	transmembrane protease, serine 13	transient receptor potential cation channel, subfamily V, member 4	0.457
TRPV4	PRDM10	ENSP00000261740	ENSP00000351686	transient receptor potential cation channel, subfamily V, member 4	PR domain containing 10	0.584
TRPV4	TMPRSS13	ENSP00000261740	ENSP00000434279	transient receptor potential cation channel, subfamily V, member 4	transmembrane protease, serine 13	0.457

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