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FAXC FAXC LETM2 LETM2 IGSF22 IGSF22 DUS1L DUS1L CCDC90B CCDC90B IER5L IER5L LETM1 LETM1 ASIC2 ASIC2 SURF4 SURF4
"CCDC90B" - coiled-coil domain containing 90B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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[Homology]
Score
CCDC90Bcoiled-coil domain containing 90B (254 aa)    
Predicted Functional Partners:
IER5L
immediate early response 5-like (404 aa)
            score_image   0.748
DUS1L
dihydrouridine synthase 1-like (S. cerevisiae); Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) (473 aa)
            score_image   0.553
IGSF22
immunoglobulin superfamily, member 22 (1326 aa)
            score_image   0.509
SURF4
surfeit 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi (269 aa)
        score_image       0.475
FAXC
failed axon connections homolog (Drosophila); May play a role in axonal development (By similarity) (409 aa)
            score_image   0.471
ASIC2
acid-sensing (proton-gated) ion channel 2; Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate (563 aa)
            score_image   0.434
LETM2
leucine zipper-EF-hand containing transmembrane protein 2 (444 aa)
        score_image   score_image   0.420
LETM1
leucine zipper-EF-hand containing transmembrane protein 1; Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization (739 aa)
        score_image   score_image   0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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