KIAA0408 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KIAA0408

KIAA0408 (694 aa)

Predicted Functional Partners:

VIM

0.625

SORBS3

0.591

GFAP

0.548

ABI3

0.485

YWHAG

0.447

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI3	KIAA0408	ENSP00000225941	ENSP00000435150	ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility	KIAA0408	0.485
GFAP	KIAA0408	ENSP00000253408	ENSP00000435150	glial fibrillary acidic protein	KIAA0408	0.548
KIAA0408	ABI3	ENSP00000435150	ENSP00000225941	KIAA0408	ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility	0.485
KIAA0408	GFAP	ENSP00000435150	ENSP00000253408	KIAA0408	glial fibrillary acidic protein	0.548
KIAA0408	SORBS3	ENSP00000435150	ENSP00000240123	KIAA0408	sorbin and SH3 domain containing 3; Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain	0.591
KIAA0408	VIM	ENSP00000435150	ENSP00000224237	KIAA0408	vimentin	0.625
KIAA0408	YWHAG	ENSP00000435150	ENSP00000306330	KIAA0408	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner	0.447
SORBS3	KIAA0408	ENSP00000240123	ENSP00000435150	sorbin and SH3 domain containing 3; Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain	KIAA0408	0.591
VIM	KIAA0408	ENSP00000224237	ENSP00000435150	vimentin	KIAA0408	0.625
YWHAG	KIAA0408	ENSP00000306330	ENSP00000435150	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner	KIAA0408	0.447

Experiments

Cooccurrence

Databases

Neighborhood

Textmining

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About