ENSG00000100890 protein (Homo sapiens)

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ENSG00000100890

mitochondrial ribonuclease P protein 3 isoform 2 (583 aa)

Predicted Functional Partners:

PSMB11

0.566

PTCD2

0.548

RPUSD4

0.527

GUF1

0.505

PTCD3

0.495

PTCD1

0.493

ENSG00000248919

0.493

METTL17

0.485

DDX28

0.483

MRPS27

0.482

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX28	ENSG00000100890	ENSP00000332340	ENSP00000440915	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	mitochondrial ribonuclease P protein 3 isoform 2	0.483
DDX28	GUF1	ENSP00000332340	ENSP00000281543	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	GUF1 GTPase homolog (S. cerevisiae); Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity)	0.578
DDX28	METTL17	ENSP00000332340	ENSP00000372445	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	methyltransferase like 17; May be a component of the mitochondrial small ribosomal subunit (By similarity)	0.666
DDX28	PTCD3	ENSP00000332340	ENSP00000254630	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation	0.443
DDX28	RPUSD4	ENSP00000332340	ENSP00000298317	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	RNA pseudouridylate synthase domain containing 4	0.576
ENSG00000100890	DDX28	ENSP00000440915	ENSP00000332340	mitochondrial ribonuclease P protein 3 isoform 2	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	0.483
ENSG00000100890	ENSG00000248919	ENSP00000440915	ENSP00000400168	mitochondrial ribonuclease P protein 3 isoform 2	ATP5J2-PTCD1 readthrough	0.493
ENSG00000100890	GUF1	ENSP00000440915	ENSP00000281543	mitochondrial ribonuclease P protein 3 isoform 2	GUF1 GTPase homolog (S. cerevisiae); Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity)	0.505
ENSG00000100890	METTL17	ENSP00000440915	ENSP00000372445	mitochondrial ribonuclease P protein 3 isoform 2	methyltransferase like 17; May be a component of the mitochondrial small ribosomal subunit (By similarity)	0.485
ENSG00000100890	MRPS27	ENSP00000440915	ENSP00000261413	mitochondrial ribonuclease P protein 3 isoform 2	mitochondrial ribosomal protein S27	0.482
ENSG00000100890	PSMB11	ENSP00000440915	ENSP00000386212	mitochondrial ribonuclease P protein 3 isoform 2	proteasome (prosome, macropain) subunit, beta type, 11; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome (By similarity). Plays a pivotal role in development of CD8-positive T cells (By similarity)	0.566
ENSG00000100890	PTCD1	ENSP00000440915	ENSP00000450995	mitochondrial ribonuclease P protein 3 isoform 2	pentatricopeptide repeat domain 1; Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3’ processing of mitochondrial tRNAs	0.493
ENSG00000100890	PTCD2	ENSP00000440915	ENSP00000308948	mitochondrial ribonuclease P protein 3 isoform 2	pentatricopeptide repeat domain 2; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function (By similarity)	0.548
ENSG00000100890	PTCD3	ENSP00000440915	ENSP00000254630	mitochondrial ribonuclease P protein 3 isoform 2	pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation	0.495
ENSG00000100890	RPUSD4	ENSP00000440915	ENSP00000298317	mitochondrial ribonuclease P protein 3 isoform 2	RNA pseudouridylate synthase domain containing 4	0.527
ENSG00000248919	ENSG00000100890	ENSP00000400168	ENSP00000440915	ATP5J2-PTCD1 readthrough	mitochondrial ribonuclease P protein 3 isoform 2	0.493
ENSG00000248919	MRPS27	ENSP00000400168	ENSP00000261413	ATP5J2-PTCD1 readthrough	mitochondrial ribosomal protein S27	0.443
ENSG00000248919	PTCD2	ENSP00000400168	ENSP00000308948	ATP5J2-PTCD1 readthrough	pentatricopeptide repeat domain 2; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function (By similarity)	0.843
ENSG00000248919	PTCD3	ENSP00000400168	ENSP00000254630	ATP5J2-PTCD1 readthrough	pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation	0.744
GUF1	DDX28	ENSP00000281543	ENSP00000332340	GUF1 GTPase homolog (S. cerevisiae); Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity	0.578

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