Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
GOLGA8F GOLGA8F TUBGCP5 TUBGCP5 NIPA1 NIPA1 ATP10A ATP10A GOLGA8G GOLGA8G PPIL6 PPIL6 KIAA1147 KIAA1147 DENND6A DENND6A SV2C SV2C AVL9 AVL9 FAM45A FAM45A
KIAA1147 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIAA1147KIAA1147; May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia (By similarity) (455 aa)    
Predicted Functional Partners:
AVL9
AVL9 homolog (S. cerevisiase); Functions in cell migration (648 aa)
            score_image   0.872
FAM45A
family with sequence similarity 45, member A (357 aa)
            score_image   0.868
DENND6A
DENN/MADD domain containing 6A; Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes (608 aa)
            score_image   0.868
SV2C
synaptic vesicle glycoprotein 2C; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity) (727 aa)
            score_image   0.681
TUBGCP5
tubulin, gamma complex associated protein 5; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (1024 aa)
            score_image   0.668
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) (329 aa)
            score_image   0.651
ATP10A
ATPase, class V, type 10A (1499 aa)
            score_image   0.579
GOLGA8G
golgin A8 family, member G (648 aa)
            score_image   0.505
GOLGA8F
golgin A8 family, member F (648 aa)
            score_image   0.505
PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) (337 aa)
            score_image   0.504
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (45%)