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PPAP2B PPAP2B LIF LIF ALAD ALAD TUSC3 TUSC3 MGAM MGAM AMY2A AMY2A ALB ALB SI SI PRDM10 PRDM10 WDTC1 WDTC1 DNAH8 DNAH8
"MGAM" - maltase-glucoamylase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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fusion edge
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protein homology
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MGAMmaltase-glucoamylase (alpha-glucosidase); May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing (1857 aa)    
Predicted Functional Partners:
AMY2A
amylase, alpha 2A (pancreatic) (511 aa)
score_image         score_image score_image   0.929
SI
sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides (1827 aa)
          score_image score_image score_image 0.901
WDTC1
WD and tetratricopeptide repeats 1 (676 aa)
            score_image   0.901
ALAD
aminolevulinate dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (330 aa)
            score_image   0.889
PRDM10
PR domain containing 10 (1160 aa)
            score_image   0.879
DNAH8
dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4695 aa)
            score_image   0.870
ALB
albumin (609 aa)
            score_image   0.870
LIF
leukemia inhibitory factor; LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes (202 aa)
            score_image   0.780
TUSC3
tumor suppressor candidate 3; Magnesium transporter. May be involved in N- glycosylation through its association with N-oligosaccharyl transferase (348 aa)
        score_image   score_image   0.773
PPAP2B
phosphatidic acid phosphatase type 2B; Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions (311 aa)
            score_image   0.748
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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