ENSG00000259075 protein (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSG00000259075

POC1B-GALNT4 readthrough (575 aa)

Predicted Functional Partners:

C1GALT1

0.915

GCNT1

0.909

ST6GALNAC1

0.906

C1GALT1C1

0.905

OVGP1

0.407

ARL11

0.405

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL11	ENSG00000259075	ENSP00000282026	ENSP00000447852	ADP-ribosylation factor-like 11; May play a role in apoptosis. May act as a tumor suppressor	POC1B-GALNT4 readthrough	0.405
ARL11	OVGP1	ENSP00000282026	ENSP00000358747	ADP-ribosylation factor-like 11; May play a role in apoptosis. May act as a tumor suppressor	oviductal glycoprotein 1, 120kDa; Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development	0.421
C1GALT1	C1GALT1C1	ENSP00000223122	ENSP00000304364	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	0.985
C1GALT1	ENSG00000259075	ENSP00000223122	ENSP00000447852	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	POC1B-GALNT4 readthrough	0.915
C1GALT1	GCNT1	ENSP00000223122	ENSP00000365920	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	0.955
C1GALT1	ST6GALNAC1	ENSP00000223122	ENSP00000156626	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.961
C1GALT1C1	C1GALT1	ENSP00000304364	ENSP00000223122	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	0.985
C1GALT1C1	ENSG00000259075	ENSP00000304364	ENSP00000447852	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	POC1B-GALNT4 readthrough	0.905
C1GALT1C1	GCNT1	ENSP00000304364	ENSP00000365920	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	0.929
C1GALT1C1	ST6GALNAC1	ENSP00000304364	ENSP00000156626	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.952
ENSG00000259075	ARL11	ENSP00000447852	ENSP00000282026	POC1B-GALNT4 readthrough	ADP-ribosylation factor-like 11; May play a role in apoptosis. May act as a tumor suppressor	0.405
ENSG00000259075	C1GALT1	ENSP00000447852	ENSP00000223122	POC1B-GALNT4 readthrough	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	0.915
ENSG00000259075	C1GALT1C1	ENSP00000447852	ENSP00000304364	POC1B-GALNT4 readthrough	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	0.905
ENSG00000259075	GCNT1	ENSP00000447852	ENSP00000365920	POC1B-GALNT4 readthrough	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	0.909
ENSG00000259075	OVGP1	ENSP00000447852	ENSP00000358747	POC1B-GALNT4 readthrough	oviductal glycoprotein 1, 120kDa; Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development	0.407
ENSG00000259075	ST6GALNAC1	ENSP00000447852	ENSP00000156626	POC1B-GALNT4 readthrough	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.906
GCNT1	C1GALT1	ENSP00000365920	ENSP00000223122	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development	0.955
GCNT1	C1GALT1C1	ENSP00000365920	ENSP00000304364	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)	0.929
GCNT1	ENSG00000259075	ENSP00000365920	ENSP00000447852	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	POC1B-GALNT4 readthrough	0.909
GCNT1	ST6GALNAC1	ENSP00000365920	ENSP00000156626	glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.936

page 1 of 2

Experiments

Cooccurrence

Databases

Neighborhood

Textmining

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About