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ACSS1 ACSS1 ACSS3 ACSS3 ALDH6A1 ALDH6A1 ACADM ACADM PCCA PCCA ECHDC1 ECHDC1 PCCB PCCB ACACB ACACB ACSS2 ACSS2 ACLY ACLY ACACA ACACA
"ACSS3" - acyl-CoA synthetase short-chain family member 3 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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[Homology]
Score
ACSS3acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) (686 aa)    
Predicted Functional Partners:
PCCB
propionyl CoA carboxylase, beta polypeptide (559 aa)
      score_image score_image score_image score_image   0.930
ACADM
acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 (425 aa)
      score_image   score_image score_image   0.924
ECHDC1
enoyl CoA hydratase domain containing 1 (307 aa)
      score_image   score_image score_image   0.920
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
score_image     score_image score_image   score_image   0.916
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
score_image     score_image score_image   score_image   0.916
ACSS2
acyl-CoA synthetase short-chain family member 2; Activates acetate so that it can be used for lipid synthesis or for energy generation (714 aa)
    score_image     score_image score_image score_image 0.916
ACSS1
acyl-CoA synthetase short-chain family member 1 (689 aa)
    score_image     score_image score_image score_image 0.915
PCCA
propionyl CoA carboxylase, alpha polypeptide (728 aa)
          score_image score_image   0.913
ALDH6A1
aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (535 aa)
          score_image     0.900
ACLY
ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine (1101 aa)
      score_image score_image   score_image   0.876
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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