node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACA | ACACB | ENSP00000344789 | ENSP00000341044 | acetyl-CoA carboxylase alpha | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.999 |
ACACA | ACADM | ENSP00000344789 | ENSP00000409612 | acetyl-CoA carboxylase alpha | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | 0.758 |
ACACA | ACLY | ENSP00000344789 | ENSP00000253792 | acetyl-CoA carboxylase alpha | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.983 |
ACACA | ACSS1 | ENSP00000344789 | ENSP00000316924 | acetyl-CoA carboxylase alpha | acyl-CoA synthetase short-chain family member 1 | 0.994 |
ACACA | ACSS2 | ENSP00000344789 | ENSP00000253382 | acetyl-CoA carboxylase alpha | acyl-CoA synthetase short-chain family member 2; Activates acetate so that it can be used for lipid synthesis or for energy generation | 0.994 |
ACACA | ACSS3 | ENSP00000344789 | ENSP00000449535 | acetyl-CoA carboxylase alpha | acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) | 0.916 |
ACACA | ALDH6A1 | ENSP00000344789 | ENSP00000450436 | acetyl-CoA carboxylase alpha | aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | 0.914 |
ACACA | ECHDC1 | ENSP00000344789 | ENSP00000436585 | acetyl-CoA carboxylase alpha | enoyl CoA hydratase domain containing 1 | 0.694 |
ACACA | PCCA | ENSP00000344789 | ENSP00000365462 | acetyl-CoA carboxylase alpha | propionyl CoA carboxylase, alpha polypeptide | 0.839 |
ACACA | PCCB | ENSP00000344789 | ENSP00000419027 | acetyl-CoA carboxylase alpha | propionyl CoA carboxylase, beta polypeptide | 0.758 |
ACACB | ACACA | ENSP00000341044 | ENSP00000344789 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acetyl-CoA carboxylase alpha | 0.999 |
ACACB | ACADM | ENSP00000341044 | ENSP00000409612 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | 0.765 |
ACACB | ACLY | ENSP00000341044 | ENSP00000253792 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.907 |
ACACB | ACSS1 | ENSP00000341044 | ENSP00000316924 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acyl-CoA synthetase short-chain family member 1 | 0.994 |
ACACB | ACSS2 | ENSP00000341044 | ENSP00000253382 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acyl-CoA synthetase short-chain family member 2; Activates acetate so that it can be used for lipid synthesis or for energy generation | 0.995 |
ACACB | ACSS3 | ENSP00000341044 | ENSP00000449535 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) | 0.916 |
ACACB | ALDH6A1 | ENSP00000341044 | ENSP00000450436 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | 0.920 |
ACACB | ECHDC1 | ENSP00000341044 | ENSP00000436585 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | enoyl CoA hydratase domain containing 1 | 0.682 |
ACACB | PCCA | ENSP00000341044 | ENSP00000365462 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | propionyl CoA carboxylase, alpha polypeptide | 0.826 |
ACACB | PCCB | ENSP00000341044 | ENSP00000419027 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | propionyl CoA carboxylase, beta polypeptide | 0.768 |