node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACB | ACADM | ENSP00000341044 | ENSP00000409612 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | 0.765 |
ACACB | ACAT1 | ENSP00000341044 | ENSP00000265838 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | 0.979 |
ACACB | ALDH1B1 | ENSP00000341044 | ENSP00000366927 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | 0.669 |
ACACB | ALDH3A2 | ENSP00000341044 | ENSP00000345774 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | aldehyde dehydrogenase 3 family, member A2; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | 0.644 |
ACACB | ALDH6A1 | ENSP00000341044 | ENSP00000450436 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | 0.920 |
ACACB | ALDH9A1 | ENSP00000341044 | ENSP00000346827 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction | 0.639 |
ACACB | ECHDC1 | ENSP00000341044 | ENSP00000436585 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | enoyl CoA hydratase domain containing 1 | 0.682 |
ACACB | EHHADH | ENSP00000341044 | ENSP00000231887 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.780 |
ACACB | PCCA | ENSP00000341044 | ENSP00000365462 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | propionyl CoA carboxylase, alpha polypeptide | 0.826 |
ACADM | ACACB | ENSP00000409612 | ENSP00000341044 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.765 |
ACADM | ACAT1 | ENSP00000409612 | ENSP00000265838 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | 0.966 |
ACADM | ALDH6A1 | ENSP00000409612 | ENSP00000450436 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | 0.922 |
ACADM | ECHDC1 | ENSP00000409612 | ENSP00000436585 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | enoyl CoA hydratase domain containing 1 | 0.962 |
ACADM | EHHADH | ENSP00000409612 | ENSP00000231887 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.993 |
ACADM | PCCA | ENSP00000409612 | ENSP00000365462 | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | propionyl CoA carboxylase, alpha polypeptide | 0.928 |
ACAT1 | ACACB | ENSP00000265838 | ENSP00000341044 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.979 |
ACAT1 | ACADM | ENSP00000265838 | ENSP00000409612 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 | 0.966 |
ACAT1 | ALDH6A1 | ENSP00000265838 | ENSP00000450436 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | 0.937 |
ACAT1 | ECHDC1 | ENSP00000265838 | ENSP00000436585 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | enoyl CoA hydratase domain containing 1 | 0.766 |
ACAT1 | EHHADH | ENSP00000265838 | ENSP00000231887 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.998 |