CEP95 protein (Homo sapiens) - STRING network view

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CEP95

centrosomal protein 95kDa (821 aa)

Predicted Functional Partners:

CSTF2T

0.509

RASGEF1A

0.507

PIBF1

0.502

ZNF729

0.450

POLG2

0.418

DCAF7

0.416

TMPRSS7

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEP95	CSTF2T	ENSP00000450461	ENSP00000332444	centrosomal protein 95kDa	cleavage stimulation factor, 3’ pre-RNA, subunit 2, 64kDa, tau variant; May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity)	0.509
CEP95	DCAF7	ENSP00000450461	ENSP00000308344	centrosomal protein 95kDa	DDB1 and CUL4 associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex	0.416
CEP95	PIBF1	ENSP00000450461	ENSP00000317144	centrosomal protein 95kDa	progesterone immunomodulatory binding factor 1; Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect	0.502
CEP95	POLG2	ENSP00000450461	ENSP00000442563	centrosomal protein 95kDa	polymerase (DNA directed), gamma 2, accessory subunit; Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA	0.418
CEP95	RASGEF1A	ENSP00000450461	ENSP00000379154	centrosomal protein 95kDa	RasGEF domain family, member 1A; Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration	0.507
CEP95	TMPRSS7	ENSP00000450461	ENSP00000411645	centrosomal protein 95kDa	transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity)	0.407
CEP95	ZNF729	ENSP00000450461	ENSP00000469582	centrosomal protein 95kDa	zinc finger protein 729; May be involved in transcriptional regulation	0.450
CSTF2T	CEP95	ENSP00000332444	ENSP00000450461	cleavage stimulation factor, 3’ pre-RNA, subunit 2, 64kDa, tau variant; May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity)	centrosomal protein 95kDa	0.509
DCAF7	CEP95	ENSP00000308344	ENSP00000450461	DDB1 and CUL4 associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex	centrosomal protein 95kDa	0.416
PIBF1	CEP95	ENSP00000317144	ENSP00000450461	progesterone immunomodulatory binding factor 1; Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect	centrosomal protein 95kDa	0.502
POLG2	CEP95	ENSP00000442563	ENSP00000450461	polymerase (DNA directed), gamma 2, accessory subunit; Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA	centrosomal protein 95kDa	0.418
RASGEF1A	CEP95	ENSP00000379154	ENSP00000450461	RasGEF domain family, member 1A; Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration	centrosomal protein 95kDa	0.507
TMPRSS7	CEP95	ENSP00000411645	ENSP00000450461	transmembrane protease, serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position (By similarity)	centrosomal protein 95kDa	0.407
ZNF729	CEP95	ENSP00000469582	ENSP00000450461	zinc finger protein 729; May be involved in transcriptional regulation	centrosomal protein 95kDa	0.450

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