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STRINGSTRING
PPP1R11 PPP1R11 POTEI POTEI POTEF POTEF PNPLA6 PNPLA6 DNAL1 DNAL1 POTEE POTEE DNAH5 DNAH5 DNAH8 DNAH8 PNPLA7 PNPLA7 DNAH10 DNAH10 POTEJ POTEJ
"DNAL1" - dynein, axonemal, light chain 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
DNAL1dynein, axonemal, light chain 1 (190 aa)    
Predicted Functional Partners:
DNAH5
dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles (4624 aa)
        score_image   score_image   0.941
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11 (126 aa)
        score_image   score_image   0.553
POTEE
POTE ankyrin domain family member E (1075 aa)
        score_image   score_image   0.526
POTEI
POTE ankyrin domain family, member I (1075 aa)
        score_image   score_image   0.526
POTEJ
POTE ankyrin domain family, member J (1038 aa)
        score_image   score_image   0.526
POTEF
POTE ankyrin domain family, member F (1075 aa)
        score_image   score_image   0.526
DNAH8
dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4695 aa)
        score_image   score_image   0.526
DNAH10
dynein, axonemal, heavy chain 10; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain (4471 aa)
        score_image   score_image   0.504
PNPLA6
patatin-like phospholipase domain containing 6; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (1375 aa)
        score_image   score_image   0.452
PNPLA7
patatin-like phospholipase domain containing 7 (1342 aa)
        score_image   score_image   0.452
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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