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STRINGSTRING
UBC UBC RAB2A RAB2A KRT86 KRT86 DSG4 DSG4 SH3TC2 SH3TC2 VSX2 VSX2
"KRT86" - keratin 86 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT86keratin 86 (486 aa)    
Predicted Functional Partners:
VSX2
visual system homeobox 2; Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity) (361 aa)
            score_image   0.812
RAB2A
RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex (212 aa)
            score_image   0.808
UBC
ubiquitin C (685 aa)
        score_image       0.633
SH3TC2
SH3 domain and tetratricopeptide repeats 2 (1288 aa)
            score_image   0.505
DSG4
desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity) (1059 aa)
            score_image   0.479
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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