| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCL1 | SECISBP2L | ENSP00000225842 | ENSP00000453854 | chemokine (C-C motif) ligand 1; Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8 | SECIS binding protein 2-like | 0.418 |
| CD1C | NSL1 | ENSP00000357152 | ENSP00000355944 | CD1c molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae); Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis | 0.472 |
| CD1C | SECISBP2L | ENSP00000357152 | ENSP00000453854 | CD1c molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells | SECIS binding protein 2-like | 0.407 |
| DYNLL2 | SECISBP2L | ENSP00000240343 | ENSP00000453854 | dynein, light chain, LC8-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity) | SECIS binding protein 2-like | 0.581 |
| EEFSEC | PSTK | ENSP00000254730 | ENSP00000357882 | eukaryotic elongation factor, selenocysteine-tRNA-specific; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | phosphoseryl-tRNA kinase; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis (By similarity) | 0.911 |
| EEFSEC | SECISBP2L | ENSP00000254730 | ENSP00000453854 | eukaryotic elongation factor, selenocysteine-tRNA-specific; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | SECIS binding protein 2-like | 0.797 |
| EEFSEC | TRNAU1AP | ENSP00000254730 | ENSP00000362936 | eukaryotic elongation factor, selenocysteine-tRNA-specific; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | tRNA selenocysteine 1 associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity) | 0.941 |
| FAM169A | SECISBP2L | ENSP00000373808 | ENSP00000453854 | family with sequence similarity 169, member A | SECIS binding protein 2-like | 0.533 |
| NSL1 | CD1C | ENSP00000355944 | ENSP00000357152 | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae); Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis | CD1c molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells | 0.472 |
| NSL1 | SECISBP2L | ENSP00000355944 | ENSP00000453854 | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae); Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis | SECIS binding protein 2-like | 0.501 |
| PSTK | EEFSEC | ENSP00000357882 | ENSP00000254730 | phosphoseryl-tRNA kinase; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis (By similarity) | eukaryotic elongation factor, selenocysteine-tRNA-specific; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | 0.911 |
| PSTK | SECISBP2L | ENSP00000357882 | ENSP00000453854 | phosphoseryl-tRNA kinase; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis (By similarity) | SECIS binding protein 2-like | 0.461 |
| PSTK | TRNAU1AP | ENSP00000357882 | ENSP00000362936 | phosphoseryl-tRNA kinase; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis (By similarity) | tRNA selenocysteine 1 associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity) | 0.819 |
| SECISBP2L | CCL1 | ENSP00000453854 | ENSP00000225842 | SECIS binding protein 2-like | chemokine (C-C motif) ligand 1; Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8 | 0.418 |
| SECISBP2L | CD1C | ENSP00000453854 | ENSP00000357152 | SECIS binding protein 2-like | CD1c molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells | 0.407 |
| SECISBP2L | DYNLL2 | ENSP00000453854 | ENSP00000240343 | SECIS binding protein 2-like | dynein, light chain, LC8-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity) | 0.581 |
| SECISBP2L | EEFSEC | ENSP00000453854 | ENSP00000254730 | SECIS binding protein 2-like | eukaryotic elongation factor, selenocysteine-tRNA-specific; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | 0.797 |
| SECISBP2L | FAM169A | ENSP00000453854 | ENSP00000373808 | SECIS binding protein 2-like | family with sequence similarity 169, member A | 0.533 |
| SECISBP2L | NSL1 | ENSP00000453854 | ENSP00000355944 | SECIS binding protein 2-like | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae); Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis | 0.501 |
| SECISBP2L | PSTK | ENSP00000453854 | ENSP00000357882 | SECIS binding protein 2-like | phosphoseryl-tRNA kinase; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis (By similarity) | 0.461 |
Share
