Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | GOLGA8F | golgin A8 family, member F (648 aa) | ||||||||||||
Predicted Functional Partners:
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 | ENSG00000235153 | Uncharacterized protein; cDNA FLJ52611 (175 aa) |
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0.720 | ||||||||||
 | ENSG00000233812 | Uncharacterized protein; cDNA FLJ52611 (175 aa) |
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0.720 | ||||||||||
 | NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2; Acts as a selective Mg(2+) transporter (By similarity) (360 aa) |
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0.580 | ||||||||||
 | ENSG00000268531 | Putative uncharacterized protein DKFZp547L112 (226 aa) |
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0.513 | ||||||||||
 | KIAA1147 | KIAA1147; May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia (By similarity) (455 aa) |
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0.505 | ||||||||||
 | C3orf30 | chromosome 3 open reading frame 30 (536 aa) |
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0.503 | ||||||||||
 | NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) (329 aa) |
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0.473 | ||||||||||
 | ZNF43 | zinc finger protein 43; May be involved in transcriptional regulation (809 aa) |
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0.472 | ||||||||||
 | MFSD6L | major facilitator superfamily domain containing 6-like (586 aa) |
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0.470 | ||||||||||
 | WHAMM | WAS protein homolog associated with actin, golgi membranes and microtubules; Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex (809 aa) |
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0.450 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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