node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALG2 | COG3 | ENSP00000417764 | ENSP00000258654 | asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | 0.470 |
ALG2 | COG4 | ENSP00000417764 | ENSP00000315775 | asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | 0.403 |
ALG2 | ENSG00000260371 | ENSP00000417764 | ENSP00000454500 | asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate | Uncharacterized protein | 0.744 |
COG1 | COG3 | ENSP00000299886 | ENSP00000258654 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | 0.999 |
COG1 | COG4 | ENSP00000299886 | ENSP00000315775 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | 0.999 |
COG1 | COG6 | ENSP00000299886 | ENSP00000397441 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | 0.999 |
COG1 | ENSG00000260371 | ENSP00000299886 | ENSP00000454500 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) | Uncharacterized protein | 0.778 |
COG3 | ALG2 | ENSP00000258654 | ENSP00000417764 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate | 0.470 |
COG3 | COG1 | ENSP00000258654 | ENSP00000299886 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) | 0.999 |
COG3 | COG4 | ENSP00000258654 | ENSP00000315775 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | 0.999 |
COG3 | COG6 | ENSP00000258654 | ENSP00000397441 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | 0.999 |
COG3 | ENSG00000260371 | ENSP00000258654 | ENSP00000454500 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | Uncharacterized protein | 0.961 |
COG3 | GOSR1 | ENSP00000258654 | ENSP00000225724 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.716 |
COG3 | VPS52 | ENSP00000258654 | ENSP00000409952 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | vacuolar protein sorting 52 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD | 0.726 |
COG4 | ALG2 | ENSP00000315775 | ENSP00000417764 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate | 0.403 |
COG4 | COG1 | ENSP00000315775 | ENSP00000299886 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) | 0.999 |
COG4 | COG3 | ENSP00000315775 | ENSP00000258654 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport | 0.999 |
COG4 | COG6 | ENSP00000315775 | ENSP00000397441 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | 0.999 |
COG4 | ENSG00000260371 | ENSP00000315775 | ENSP00000454500 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | Uncharacterized protein | 0.963 |
COG4 | GOSR1 | ENSP00000315775 | ENSP00000225724 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.454 |